Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity

• Published in: Journal of internal medicine Vol. 271; no. 2; pp. 183 - 192
• Main Authors: Trumpfheller, C., Longhi, M. P., Caskey, M., Idoyaga, J., Bozzacco, L., Keler, T., Schlesinger, S. J., Steinman, R. M.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.02.2012; Blackwell
• Subjects: adjuvant; Adjuvants, Immunologic - pharmacology; Animals; Antigens, CD - immunology; Biological and medical sciences; Carboxymethylcellulose Sodium - analogs & derivatives; Carboxymethylcellulose Sodium - pharmacology; CD8-Positive T-Lymphocytes - immunology; cross-presentation; DEC-205; dendritic cells; Dendritic Cells - immunology; Gene Products, gag - immunology; General aspects; Human immunodeficiency virus; Humans; Immunity, Cellular - immunology; Interferon Inducers - pharmacology; Lectins, C-Type - immunology; Macaca mulatta; Medical sciences; Mice; Minor Histocompatibility Antigens; Mycobacterium; Poly I-C - pharmacology; Polylysine - analogs & derivatives; Polylysine - pharmacology; Prevention and actions; protein vaccine; Public health. Hygiene; Public health. Hygiene-occupational medicine; Receptors, Cell Surface - immunology; Signal Transduction - immunology; T cells; T-Lymphocytes - immunology; Toll-Like Receptors - immunology; Vaccines - immunology; USA, New York; Dendritic cell; Technical progress; Targeting; DEC-205; protein vaccine; Antigen cross presentation; Vaccine; Protein A; T cells; Immunity; Medicine; Prevention; Immunoprophylaxis; Target; dendritic cells; cross-presentation; Antigen presenting cell; T-Lymphocyte; Adjuvant

.  Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM (The Rockefeller University, New York, NY; and Celldex Therapeutics, Phillipsburg, NJ; USA). Dendritic cell‐targeted protein vaccines: a novel approach to induce T‐cell immunity (Review). J Intern Med...