Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription - Chen, Qinjunjie; Wang, Haibo; Li, Zheng; Li, Fengwei; Liang, Leilei; Zou, Yiran; Shen, Hao; Li, Jun; Xia, Yong; Cheng, Zhangjun; Yang, Tian; Wang, Kui; et al. (Journal of Hepatology, 2022)
Keywords: Actinin; Actinin - adverse effects; Aged; Carcinogenesis; Carcinogenesis - genetics; Cholangiocarcinoma; Cholangiocarcinoma - etiology; Cholangiocarcinoma - genetics; Chromatin; circACTN4; Circular RNA; Disease Progression; DNA microarrays; Electrophoretic mobility; Female; Frizzled protein; Frizzled Receptors; Frizzled Receptors - drug effects; Frizzled Receptors - metabolism; FZD7; Hippo; Humans; Immunoprecipitation; Intrahepatic cholangiocarcinoma; Liver cancer; Male; Mass spectroscopy; Metastases; Metastasis; Middle Aged; miRNA; Prognosis; Proportional Hazards Models; Protein purification; Proteins; Ribonucleic acid; RNA; RNA, Circular; RNA, Circular - adverse effects; RNA-binding protein; Statistics, Nonparametric; Therapeutic targets; Transcription; Tumors; Wnt; Wnt protein; Wnt Signaling Pathway; Wnt Signaling Pathway - drug effects; Xenografts; Y-Box-Binding Protein 1; Y-Box-Binding Protein 1 - adverse effects; Y-Box-Binding Protein 1 - drug effects; YAP1; Yes-associated protein; β-Catenin; YAP1; Wnt; circACTN4; FZD7; Hippo; Intrahepatic cholangiocarcinoma