Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease - Seppänen, Allan; Pikkarainen, Maria; Hartikainen, Päivi; Hofmann, Silke C.; Majamaa, Kari; Alafuzoff, Irina (Brain research, 2009)
Keywords: Adaptor Proteins, Signal Transducing - genetics; Adaptor Proteins, Signal Transducing - metabolism; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis - genetics; Amyotrophic Lateral Sclerosis - metabolism; Amyotrophic Lateral Sclerosis - physiopathology; Autoantigens - genetics; Autoantigens - metabolism; Biological and medical sciences; Biomarkers - analysis; Biomarkers - metabolism; Brain - metabolism; Brain - pathology; Brain - physiopathology; Cerebellum - metabolism; Cerebellum - pathology; Cerebellum - physiopathology; Cerebrospinal fluid. Meninges. Spinal cord; Collagen Type XVII; Collagen XVII; Comorbidity; Cytoskeleton - metabolism; Cytoskeleton - pathology; Dermatologi och venerologi, klinisk genetik, invärtesmedicin; Dermatology and venerology,clinical genetics, internal medicine; Female; Frontal Lobe - metabolism; Frontal Lobe - pathology; Frontal Lobe - physiopathology; Hippocampus - metabolism; Hippocampus - pathology; Hippocampus - physiopathology; Humans; Immunohistochemistry; Internal medicine; Invärtesmedicin; Male; Medical sciences; MEDICIN; MEDICINE; Middle Aged; Morfologi, cellbiologi, patologi; Morphology, cell biology, pathology; Motor neuron disease; Motor Neuron Disease - genetics; Motor Neuron Disease - metabolism; Motor Neuron Disease - physiopathology; Nervous system (semeiology, syndromes); Neurocognitive Disorders - metabolism; Neurocognitive Disorders - pathology; Neurocognitive Disorders - physiopathology; Neurologi; Neurology; Neurons - metabolism; Neurons - pathology; Non-Fibrillar Collagens - genetics; Non-Fibrillar Collagens - metabolism; p62; Pathology; Patologi; Sequestosome-1 Protein; coll XVII; MND; NCI; PMA; Collagen XVII; NT; TDP-43; Motor neuron disease; ALS; CNS; IR; p62; motor neuron disease; neuronal cytoplasmic inclusions; progressive muscular atrophy; amyotrophic lateral sclerosis; central nervous system; immunoreactive; trans-activating responsive sequence DNA-binding protein 43; neurites; ubiquitin-binding protein p62/sequestosome 1; collagen XVII, FTLD-U/ALS, frontotemporal lobar degeneration with ubiquitinated inclusions and amyotrophic lateral sclerosis, IHC, immunohistochemistry; Human; Ubiquitin; Nervous system diseases; Glycoprotein; Gene expression; Binding protein; Collagen; Central nervous system disease; Degenerative disease; Spinal cord disease