High expression of oncogene cadherin-6 correlates with tumor progression and a poor prognosis in gastric cancer

• Published in: Cancer cell international Vol. 21; no. 1; pp. 1 - 493
• Main Authors: Zhao, Zongxian, Li, Shuliang, Li, Shilong, Wang, Jun, Lin, Hai, Fu, Weihua
• Format: Journal Article
• Language: English
• Published: London BioMed Central 16.09.2021; BMC
• Subjects: Biomarkers; Cadherin-6; Cadherins; Cancer therapies; Datasets; Diagnosis; Extracellular matrix; Gastric cancer; Gene expression; Gene set enrichment analysis; Genomes; Hospitals; Lymphatic system; Medical prognosis; Metastasis; Morphogenesis; Oncogene; Oncogenes; Ovaries; Oxidative metabolism; Oxidative phosphorylation; Patients; Pentose phosphate pathway; Phosphorylation; Polymerase chain reaction; Primary Research; Prognosis; Regression analysis; Risk factors; Statistical analysis; Survival; Survival analysis; Tricarboxylic acid cycle; Tumor progression; Tumors; Beijing China; China

Abstract Background Gastric cancer (GC) is one of the most common and fatal cancers worldwide. Effective biomarkers to aid the early diagnosis of GC, as well as predict the course of disease, are urgently needed. Hence, we explored the role and function of cadherin-6 (CDH6) in the diagnosis and prog...