Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice - Baek, Ae Rin; Hong, Jisu; Song, Ki Sung; Jang, An Soo; Kim, Do Jin; Chin, Su Sie; Park, Sung Woo (Experimental & molecular medicine, 2020)
Keywords: 14; 14/19; 59; 631/250; 64/60; 692/699; 82; 82/51; Aging; Alveoli; Animals; Apoptosis; Autophagy; Autophagy - drug effects; Biomarkers; Biomedical and Life Sciences; Biomedicine; Bleomycin; Bleomycin - adverse effects; Cell Death; Cellular Senescence - drug effects; Collagen; Cytokines - metabolism; Disease Models, Animal; Endoplasmic reticulum; Endoplasmic Reticulum Stress - drug effects; Epithelial cells; Fibroblasts; Fibroblasts - drug effects; Fibroblasts - metabolism; Fibrosis; Inflammation; Inflammation Mediators; Lung diseases; Lungs; Medical Biochemistry; Mice; Molecular Medicine; Oxidative stress; Phagocytosis; Protective Agents - pharmacology; Protein folding; Pulmonary fibrosis; Pulmonary Fibrosis - drug therapy; Pulmonary Fibrosis - etiology; Pulmonary Fibrosis - metabolism; Pulmonary Fibrosis - pathology; Senescence; Spermidine; Spermidine - pharmacology; Stem Cells; 생화학