Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing

• Published in: Journal of nanobiotechnology Vol. 20; no. 1; pp. 1 - 19
• Main Authors: Huang, Xingtai, Wang, Qirui, Mao, Runyi, Wang, Zeying, Shen, Steve G.F., Mou, Juan, Dai, Jiewen
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 26.07.2022; BioMed Central; BMC
• Subjects: Angiogenesis; Biocompatibility; Biological activity; Biomedical materials; Collagen; Composite scaffolds; Contact angle; Diabetes; Diabetes mellitus; Diabetes therapy; Diabetic wound healing; Electrospun fibers; Embedding; Fibers; Fourier transforms; Health aspects; Hypoxia-inducible factor 1a; Insulation; Laboratory animals; Methods; Nanostructure; Polycaprolactone; Polymers; Scaffolds; Scanning electron microscopy; Signal transduction; Skin; Spectrum analysis; Tissue engineering; Vascular endothelial growth factor; Vascularization; Vermiculite; Vermiculite nanosheets; Wound healing; China; United States > US

Promoting diabetic wound healing is still a challenge, and angiogenesis is believed to be essential for diabetic wound healing. Vermiculite is a natural clay material that is very easy to obtain and exhibits excellent properties of releasing bioactive ions, buffering pH, adsorption, and heat insulat...