Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases - Figini, Matteo; Alexander, Daniel C.; Redaelli, Veronica; Fasano, Fabrizio; Grisoli, Marina; Baselli, Giuseppe; Gambetti, Pierluigi; Tagliavini, Fabrizio; Bizzi, Alberto (NeuroImage clinical, 2015)
Keywords: Adult; Aged; Aged, 80 and over; Biophysical models; Brain - pathology; Brain Mapping - methods; Creutzfeldt–Jakob disease; Diffusion Magnetic Resonance Imaging; Diffusion MRI; Female; Humans; Image Interpretation, Computer-Assisted - methods; Male; Middle Aged; Models, Theoretical; Prion disease; Prion Diseases - pathology; Radiology; Regular; Spongiform degeneration; ADC; Prion disease; MPRAGE; PrPSc; Biophysical models; CNR; EEG; GSS; RPE; SS-SE; FOV; ROI; TE; PrPC; TI; Spongiform degeneration; DWI; Diffusion MRI; CJD; BIC; Creutzfeldt–Jakob disease; TR; EPI; sCJD; inversion time; diffusion weighted imaging; PrP C; PrP Sc; contrast to noise ratio; sporadic Creutzfeldt–Jakob disease; apparent diffusion coefficient; magnetization-prepared rapid acquisition gradient-echo; prion protein scrapie; echo time; rapidly progressive encephalopathy; Gerstmann–Sträussler–Scheinker syndrome; single shot spin-echo; repetition time; field of view; electroencephalogram; region of interest; echo-planar imaging; prion protein cellular; Bayesian information criterion; PrPC, prion protein cellular; FOV, field of view; TR, repetition time; DWI, diffusion weighted imaging; EEG, electroencephalogram; CJD, Creutzfeldt–Jakob disease; RPE, rapidly progressive encephalopathy; ADC, apparent diffusion coefficient; ROI, region of interest; CNR, contrast to noise ratio; sCJD, sporadic Creutzfeldt–Jakob disease; TE, echo time; GSS, Gerstmann–Sträussler–Scheinker syndrome; SS-SE, single shot spin-echo; BIC, Bayesian information criterion; EPI, echo-planar imaging; PrPSc, prion protein scrapie; MPRAGE, magnetization-prepared rapid acquisition gradient-echo; TI, inversion time