[123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods

• Published in: EJNMMI physics Vol. 4; no. 1; pp. 8 - 16
• Main Authors: Tossici-Bolt, Livia, Dickson, John C., Sera, Terez, Booij, Jan, Asenbaun-Nan, Susanne, Bagnara, Maria C., Borght, Thierry Vander, Jonsson, Cathrine, de Nijs, Robin, Hesse, Swen, Koulibaly, Pierre M., Akdemir, Umit O., Koole, Michel, Tatsch, Klaus, Varrone, Andrea
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 28.01.2017; Springer Nature B.V
• Subjects: Applied and Technical Physics; Attenuation; Calibration; Collimation; Collimators; Computational Mathematics and Numerical Analysis; Dopamine; Engineering; Image acquisition; Image reconstruction; Imaging; Medicine; Medicine & Public Health; Nuclear Medicine; Original Research; Penetration; Radiology; Scattering; Reconstruction; Quantification; I; FP-CIT; Calibration; Specific binding ratio; SPECT; 123I

Background [ 123 I]FP-CIT is a well-established radiotracer for the diagnosis of dopaminergic degenerative disorders. The European Normal Control Database of DaTSCAN (ENC-DAT) of healthy controls has provided age and gender-specific reference values for the [ 123 I]FP-CIT specific binding ratio (SBR...