Strength Training Prevents Hyperinsulinemia, Insulin Resistance, and Inflammation Independent of Weight Loss in Fructose-Fed Animals

• Published in: Scientific reports Vol. 6; no. 1; p. 31106
• Main Authors: Botezelli, José D., Coope, Andressa, Ghezzi, Ana C., Cambri, Lucieli T., Moura, Leandro P., Scariot, Pedro P. M., Gaspar, Rodrigo Stellzer, Mekary, Rania A., Ropelle, Eduardo Rochete, Pauli, José Rodrigo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 04.08.2016; Nature Publishing Group
• Subjects: 14/19; 631/443/319/1642/2037; 692/163/2743/2037; 82/29; Animals; Blood Glucose - metabolism; Body weight loss; Diet; Dietary Carbohydrates - administration & dosage; Dietary Carbohydrates - adverse effects; Exercise; Fructose; Fructose - administration & dosage; Fructose - adverse effects; Homeostasis; Humanities and Social Sciences; Hyperinsulinemia; Hyperinsulinism - blood; Hyperinsulinism - prevention & control; Hypertriglyceridemia - etiology; Inflammation; Inflammation - prevention & control; Insulin; Insulin Resistance; JNK protein; Liver; Liver - metabolism; Liver - pathology; Male; Metabolic Diseases - etiology; Metabolic Diseases - physiopathology; Metabolic Diseases - prevention & control; Metabolic disorders; multidisciplinary; NF-κB protein; Phosphorylation; Physical Conditioning, Animal - methods; Physical fitness; Rats; Rats, Wistar; Resistance Training; Rodents; Science; Sports training; Strength training; Training; Transcription factors; Triglycerides; Weight Loss

The aim of this study was to compare the effects of aerobic, strength, and combined training on metabolic disorders induced by a fructose-rich diet. Wistar rats (120 days old) were randomized into five groups (n = 8–14): C (control diet and sedentary), F (fed the fructose-rich diet and sedentary), F...