Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism - Kim, Kyoung-Shim; Kang, Young-Mi; Kang, Young; Park, Tae-Shin; Park, Hye-Yeon; Kim, Yoon-Jung; Han, Baek-Soo; Kim, Chun-Hyung; Lee, Chul-Ho; Ardayfio, Paul A.; Han, Pyung-Lim; Jung, Bong-Hyun; et al. (Brain research, 2014)
Keywords: Adult and adolescent clinical studies; Anhedonia - drug effects; Animals; Antidepressive Agents - therapeutic use; Biological and medical sciences; Brain - metabolism; Brain - pathology; c-Fos; Comorbidity; Corticosterone - blood; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Depression; Depressive Disorder - drug therapy; Depressive Disorder - genetics; Depressive Disorder - psychology; Dietary Sucrose; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Female; Gene Expression Regulation; Genes, fos; Homeodomain Proteins - genetics; Imipramine - therapeutic use; Male; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Knockout; Mood disorders; Nerve Tissue Proteins - biosynthesis; Nerve Tissue Proteins - genetics; Neurology; Parkinsonian Disorders - genetics; Parkinsonian Disorders - psychology; Parkinson׳s disease; Proto-Oncogene Proteins c-fos - biosynthesis; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Restraint, Physical; Stress; Stress, Psychological - complications; Transcription Factors - deficiency; Transcription Factors - genetics; c-Fos; Depression; Parkinson׳s disease; Stress; Mood disorder; Animal model; Nervous system diseases; Parkinson's disease; fos Gene; Rodentia; Parkinson disease; Cerebral disorder; Parkinsonism; Vertebrata; Concomitant disease; Mammalia; Mouse; Animal; C-Onc gene; Central nervous system disease; Genetics; Degenerative disease; Protooncogene; Extrapyramidal syndrome; Immediate early gene