Left ventricular non-compaction cardiomyopathy associated with the PRKAG2 mutation

• Published in: BMC medical genomics Vol. 15; no. 1; pp. 1 - 8
• Main Authors: Zhang, Jing, Han, Xiu, Lu, Qun, Feng, Yunfei, Ma, Aiqun, Wang, Tingzhong
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 11.10.2022; BioMed Central; BMC
• Subjects: AMP-activated protein kinase; Analysis; Angina pectoris; Cardiac arrhythmia; Cardiomyopathy; Cardiovascular diseases; Causes of; Compaction; Deoxyribonucleic acid; Diagnosis; Disease; DNA; Electrocardiography; Gene mutation; Gene mutations; Genetic analysis; Genetic aspects; Genomes; Heart; Heart diseases; Hospitals; Kinases; Left ventricular non-compaction cardiomyopathy; Mutation; Next generation sequencing; Phenotypes; Proteins; Sinuses; Ultrasonic imaging; Ventricle; China

Left ventricular non-compaction cardiomyopathy (LVNC) is one of the most common inherited cardiovascular diseases. The genetic backgrounds of most LVNC patients are not fully understood. We collected clinical data, family histories, and blood samples and performed genetic analysis using next-generat...