Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine - Cabungcal, Jan-Harry; Steullet, Pascal; Kraftsik, Rudolf; Cuenod, Michel; Do, Kim Q. (Biological psychiatry (1969), 2013)
Keywords: Acetylcysteine - pharmacology; Adult and adolescent clinical studies; Age Factors; Animals; Anterior cingulate cortex; Antioxidants - pharmacology; Biological and medical sciences; Cell Proliferation - drug effects; gene-environment interactions; glutamate cysteine ligase; Glutamate-Cysteine Ligase - genetics; glutathione; Glutathione - biosynthesis; Gyrus Cinguli - drug effects; Gyrus Cinguli - growth & development; Gyrus Cinguli - metabolism; Interneurons - drug effects; Interneurons - metabolism; Male; Medical sciences; Mice; Mice, Knockout; Oxidative Stress - drug effects; Oxidative Stress - genetics; Oxidative Stress - physiology; parvalbumin; Parvalbumins - metabolism; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Schizophrenia; schizophrenia; Anterior cingulate cortex; gene-environment interactions; glutathione; parvalbumin; glutamate cysteine ligase; Oxidative stress; Calcium; Central nervous system; Acetylcysteine; Schizophrenia; Environmental factor; Inorganic element; Encephalon; Interneuron; Psychosis; Binding protein; Cingulate cortex; Ligases; Glutathione; Glutamate-cysteine ligase; Thiol; Carbon-nitrogen ligases; Enzyme; Parvalbumin; Mucolytic; Genotype environment interaction; Early