Search for genetic variants of the SYNTAXIN 1A (STX1A) gene: the -352 A>T variant in the STX1A promoter associates with impaired glucose metabolism in an Italian obese population - Romeo, S; Sentinelli, F; Cavallo, M.G; Leonetti, F; Fallarino, M; Mariotti, S; Baroni, M (International Journal of Obesity, 2008)
Keywords: Adult; Aged; Biological and medical sciences; Blood Glucose; Blood Glucose - metabolism; cohort studies; Diabetes; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 2 - genetics; Diabetes. Impaired glucose tolerance; disease resistance; Electrophoretic Mobility Shift Assay; Endocrine pancreas. Apud cells (diseases); Endocrinology; Endocrinopathies; Epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Evaluation; Female; Gene Frequency; genes; Genetic aspects; Genetic Predisposition to Disease; Genetic variance; Genetic Variation; genetics; genotype; Glucose; Glucose Intolerance; Glucose Intolerance - genetics; Glucose metabolism; glucose tolerance; Glucose Tolerance Test; Health aspects; Health Promotion and Disease Prevention; Humans; Insulin resistance; insulin secretion; Internal Medicine; Italy; Logistic Models; Male; Medical sciences; Medicine; Medicine & Public Health; men; Metabolic Diseases; Metabolism; Middle Aged; molecular sequence data; Obesity; Obesity - genetics; original-article; Overweight; Overweight - genetics; Overweight persons; Polymorphism; promoter regions; Promoter Regions, Genetic; Promoter Regions, Genetic - genetics; Proteins; Public Health; Risk factors; single nucleotide polymorphism; Syntaxin 1; Syntaxin 1 - genetics; Tumors. Hypoglycemia; Type 2 diabetes; White people; women; Italy; Europe; Rome Italy; SYNTAXIN 1A; diabetes mellitus; insulin secretion; human insulinoma; EMSA; SNARE; Endocrinopathy; Pancreatic hormone; Genetic variability; SNARE protein; Insulinoma; Glucose; Secretory tumor; Promoter; Gene; Genetics; Benign neoplasm; Nutritional status; Pancreatic disease; Human; Obesity; Nutrition; Secretion; Diabetes mellitus; Genetic variant; Nutrition disorder; Genotype