NUCOME: A comprehensive database of nucleosome organization referenced landscapes in mammalian genomes

• Published in: BMC bioinformatics Vol. 22; no. 1; pp. 1 - 15
• Main Authors: Chen, Xiaolan, Yang, Hui, Liu, Guifen, Zhang, Yong
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 13.06.2021; BioMed Central; BMC
• Subjects: Binding sites; Biological research; Biology, Experimental; Datasets; Design and construction; DNA methylation; Electronic data processing; Filtration; Gene expression; Genetic transcription; Genomes; Mammals; Methods; MNase; Nucleosome; Nucleosomes; Online databases; Quality assessment; Quality control; Structure; Transcription factors; Transcriptional regulation; China

Nucleosome organization is involved in many regulatory activities in various organisms. However, studies integrating nucleosome organization in mammalian genomes are very limited mainly due to the lack of comprehensive data quality control (QC) assessment and uneven data quality of public data sets....