Carbon nanotube filler enhances incinerated thermoplastics-induced cytotoxicity and metabolic disruption in vitro

• Published in: Particle and fibre toxicology Vol. 17; no. 1; pp. 1 - 21
• Main Authors: Coyle, Jayme P., Derk, Raymond C., Kornberg, Tiffany G., Singh, Dilpreet, Jensen, Jake, Friend, Sherri, Mercer, Robert, Stueckle, Todd A., Demokritou, Philip, Rojanasakul, Yon, Rojanasakul, Liying W.
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 12.08.2020; BioMed Central; BMC
• Subjects: Additives; Carbon nanotubes; Cell culture; Cell death; Cell lines; Cytotoxicity; Efficiency; Epithelial cells; Fillers; Genotoxicity; Health aspects; In vitro; Incinerated thermoplastics; Incineration; Materials; Membrane potential; Metabolism; Microscopy; Mitochondria; Nano-enabled composites; Nanomaterials; Nanotechnology; Nanotubes; Organic chemicals; Pathological effects; Polycarbonate; Polycarbonate resins; Polycyclic aromatic hydrocarbons; Polymer composites; Polymer matrix composites; Polyurethane; Polyurethane resins; Reactive oxygen species; Respiratory tract; Sensitivity analysis; Sensitivity enhancement; Thermal cycling; Thermoplastic resins; Thermoplastics; Toxicity; Ultrafines; United States

Engineered nanomaterials are increasingly being incorporated into synthetic materials as fillers and additives. The potential pathological effects of end-of-lifecycle recycling and disposal of virgin and nano-enabled composites have not been adequately addressed, particularly following incineration....