Fetal and adult liver stem cells for liver regeneration and tissue engineering

• Published in: Journal of cellular and molecular medicine Vol. 10; no. 3; pp. 577 - 587
• Main Authors: Fiegel, H. C., Lange, Claudia, Kneser, U., Lambrecht, W., Zander, A. R., Rogiers, X., Kluth, D.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.2006; John Wiley & Sons, Inc; John Wiley & Sons, Ltd
• Subjects: Animals; Bone marrow; Bone Marrow Cells - cytology; Bone marrow transplantation; Cell Culture Techniques - methods; Cell differentiation; Cell fusion; Embryo cells; Embryogenesis; Environmental conditions; Environmental engineering; Extracellular matrix; fetal stem cells; Fetuses; Gene expression; Growth factors; Hematopoietic stem cells; hepatic tissue engineering; Hepatocytes; Hepatocytes - cytology; Humans; Immobilized cells; Liver; Liver - cytology; Liver - embryology; Liver - metabolism; liver cell transplantation; Liver Diseases - therapy; Liver Regeneration; liver stem cells; Liver transplantation; Mesenchymal stem cells; Regeneration; stem cell culture; Stem cell research; Stem cell transplantation; Stem cells; Stem Cells - cytology; Tissue engineering; Tissue Engineering - instrumentation; Tissue Engineering - methods; Tissue Engineering Review Series; Transplantation

For the development of innovative cell‐based liver directed therapies, e.g. liver tissue engineering, the use of stem cells might be very attractive to overcome the limitation of donor liver tissue. Liver specific differentiation of embryonic, fetal or adult stem cells is currently under investigati...