A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

• Published in: The Journal of physiology Vol. 593; no. 17; pp. 3991 - 4010
• Main Authors: Hey‐Mogensen, Martin, Gram, Martin, Jensen, Martin Borch, Lund, Michael Taulo, Hansen, Christina Neigaard, Scheibye‐Knudsen, Morten, Bohr, Vilhelm A., Dela, Flemming
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.09.2015; John Wiley & Sons, Ltd
• Subjects: Adult; Aged; Aging - physiology; Cell Respiration; DNA, Mitochondrial - genetics; Humans; Hydrogen Peroxide - metabolism; Male; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria, Muscle - metabolism; Mitochondria, Muscle - physiology; Muscle; Muscle, Skeletal - metabolism; Muscle, Skeletal - physiology; Myosin Heavy Chains - metabolism; Young Adult

Key points The present study utilized a novel method aiming to investigate mitochondrial function in human skeletal muscle at submaximal levels and at a predefined membrane potential. The effect of age and training status was investigated using a cross‐sectional design. Ageing was found to be relate...