Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens

• Published in: The Prostate Vol. 73; no. 7; pp. 770 - 777
• Main Authors: Mak, Tim N., Yu, Shu-Han, De Marzo, Angelo M., Brüggemann, Holger, Sfanos, Karen S.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.05.2013; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Gram-Positive Bacterial Infections - microbiology; Humans; infection; inflammation; Male; Middle Aged; MLST; Multilocus Sequence Typing - methods; Propionibacterium; Propionibacterium - genetics; Propionibacterium - isolation & purification; Propionibacterium acnes; Propionibacterium acnes - genetics; Propionibacterium acnes - isolation & purification; Prostate - microbiology; prostate cancer; Prostatectomy; Prostatic Neoplasms - microbiology; Sequence Analysis, DNA

BACKGROUND Inflammation is commonly observed in radical prostatectomy specimens, and evidence suggests that inflammation may contribute to prostate carcinogenesis. Multiple microorganisms have been implicated in serving as a stimulus for prostatic inflammation. The pro‐inflammatory anaerobe, Propion...