Beneficial immune-modulatory effects of the N-163 strain of Aureobasidium pullulans-produced 1,3-1,6 Beta glucans in Duchenne muscular dystrophy: Results of an open-label, prospective, exploratory case-control clinical study

• Published in: IBRO neuroscience reports Vol. 15; pp. 90 - 99
• Main Authors: Raghavan, Kadalraja, Dedeepiya, Vidyasagar Devaprasad, Srinivasan, Subramaniam, Pushkala, Subramanian, Bharatidasan, Sudhakar S., Ikewaki, Nobunao, Iwasaki, Masaru, Senthilkumar, Rajappa, Preethy, Senthilkumar, Abraham, Samuel J.K.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.12.2023; Elsevier
• Subjects: Beta glucan; Disease modifying agent; Duchenne muscular dystrophy; Dystrophin; Fibrosis; Inflammation; N-163; Short Communication; NSAA; Beta glucan; CK; Inflammation; LeCR; NASH; 6MWT; N-163; LGMD; TNF-α; NLR; Disease modifying agent; Duchenne muscular dystrophy; Fibrosis; DMD; LCR; Dystrophin; MRC

This exploratory case-control study is to evaluate the effects of supplementation of Aureobasidium pullulans-N-163 strain produced 1,3–1,− 6 beta glucan in young patients with Duchenne muscular dystrophy (DMD). Twenty-seven male subjects aged 5–19 years with DMD were included, nine in the control ar...