Catestatin: Antimicrobial Functions and Potential Therapeutics
The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternati...
Saved in:
| Published in | Pharmaceutics Vol. 15; no. 5; p. 1550 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Switzerland
MDPI AG
20.05.2023
MDPI |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA
; bCgA
) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST
aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST
(where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST
potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST
neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST
(aka cateslytin), D-bCST
, and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant "superbugs". |
|---|---|
| AbstractList | The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant “superbugs”. The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA352–372; bCgA344–364) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST1–15 aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST1–15 (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST1–15 potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST1–15 neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST1–15 (aka cateslytin), D-bCST1–15, and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant “superbugs”. The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant “superbugs”. The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA 352–372 ; bCgA 344–364 ) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST 1–15 aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST 1–15 (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST 1–15 potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST 1–15 neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST 1–15 (aka cateslytin), D-bCST 1–15 , and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant “superbugs”. The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA ; bCgA ) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST (aka cateslytin), D-bCST , and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant "superbugs". The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA352-372; bCgA344-364) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST1-15 aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST1-15 (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST1-15 potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST1-15 neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST1-15 (aka cateslytin), D-bCST1-15, and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant "superbugs".The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA352-372; bCgA344-364) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST1-15 aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST1-15 (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST1-15 potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST1-15 neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST1-15 (aka cateslytin), D-bCST1-15, and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant "superbugs". The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA[sub.352-372]; bCgA[sub.344-364]) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. Subsequently, CST was established as a pleiotropic hormone. In 2005, it was reported that N-terminal 15 amino acids of bovine CST (bCST[sub.1-15] aka cateslytin) exert antibacterial, antifungal, and antiyeast effects without showing any hemolytic effects. In 2017, D-bCST[sub.1-15] (where L-amino acids were changed to D-amino acids) was shown to exert very effective antimicrobial effects against various bacterial strains. Beyond antimicrobial effects, D-bCST[sub.1-15] potentiated (additive/synergistic) antibacterial effects of cefotaxime, amoxicillin, and methicillin. Furthermore, D-bCST[sub.1-15] neither triggered bacterial resistance nor elicited cytokine release. The present review will highlight the antimicrobial effects of CST, bCST[sub.1-15] (aka cateslytin), D-bCST[sub.1-15], and human variants of CST (Gly364Ser-CST and Pro370Leu-CST); evolutionary conservation of CST in mammals; and their potential as a therapy for antibiotic-resistant "superbugs". |
| Audience | Academic |
| Author | Das, Soumita Jati, Suborno Mahata, Sushil K Mahata, Sumana Chatterjee, Saurabh |
| AuthorAffiliation | 5 VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA 2 Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; sumahata@health.ucsd.edu 3 Department of Biomedical and Nutritional Science, University of Massachusetts Lowell, Lowell, MA 01854, USA; soumita_das@uml.edu 1 Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA; sjati@ucsd.edu 4 Department of Medicine, University of California Irvine, Irvine, CA 92697, USA; saurabhc@hs.uci.edu |
| AuthorAffiliation_xml | – name: 1 Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA; sjati@ucsd.edu – name: 3 Department of Biomedical and Nutritional Science, University of Massachusetts Lowell, Lowell, MA 01854, USA; soumita_das@uml.edu – name: 5 VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA – name: 2 Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; sumahata@health.ucsd.edu – name: 4 Department of Medicine, University of California Irvine, Irvine, CA 92697, USA; saurabhc@hs.uci.edu |
| Author_xml | – sequence: 1 givenname: Suborno surname: Jati fullname: Jati, Suborno organization: Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA – sequence: 2 givenname: Sumana surname: Mahata fullname: Mahata, Sumana organization: Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA – sequence: 3 givenname: Soumita surname: Das fullname: Das, Soumita organization: Department of Biomedical and Nutritional Science, University of Massachusetts Lowell, Lowell, MA 01854, USA – sequence: 4 givenname: Saurabh orcidid: 0000-0003-1649-7149 surname: Chatterjee fullname: Chatterjee, Saurabh organization: Department of Medicine, University of California Irvine, Irvine, CA 92697, USA – sequence: 5 givenname: Sushil K surname: Mahata fullname: Mahata, Sushil K organization: VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37242791$$D View this record in MEDLINE/PubMed |
| BookMark | eNptUk1vEzEQtVARbUN_AigSFy4p_tqszQEURS1UqgSHcrZm_ZE42tjB3kXi3zMhJWpQ7YOt8XtvPG_mkpylnDwhbxi9FkLTD7s1lC1YPw7RVtbQhjUNfUEumNZ6JjUXZ0_u5-Sq1g3FJQRTQr8i56LlkreaXZBPSxh8HWCI6eN0kYa4jbbkLkI_vR2THWJOdQrJTb_nweMzxh_WvsDukPs1eRmgr_7q8ZyQH7c3D8uvs_tvX-6Wi_uZbVoxzJybewDFwXedlg3VwQrlRde61mtFg5gDCGuVsLSVnnvGfReYDrKToJ3txITcHXRdho3ZlbiF8ttkiOZvIJeVgYIf6r3RFByoAGBlkLJjWgQIXVDeNq51TqPW54PWbuy23lksq0B_Inr6kuLarPIvwyjnVNM5Krx_VCj554j2mW2s1vc9JJ_HarjilLK25ftk7_6DbvJYEnqFKKalogrbckStACuIKWRMbPeiZtGiXVoy7N6EXD-Dwu08dg0nJESMnxCaAwFbWmvx4Vgko2Y_SObZQULe26cOHVn_xkb8ARMCypU |
| CitedBy_id | crossref_primary_10_1007_s00253_023_12884_8 crossref_primary_10_1007_s00018_023_04908_3 crossref_primary_10_1016_j_peptides_2023_171147 |
| Cites_doi | 10.1016/j.regpep.2003.10.035 10.1086/381399 10.1160/TH17-05-0349 10.1124/mol.115.102301 10.1038/ijo.2014.153 10.2217/fmb.14.66 10.1038/s41598-021-94749-6 10.1096/fj.14-259598 10.2147/DMSO.S311388 10.1242/jcs.114389 10.1161/HYPERTENSIONAHA.112.202127 10.1016/j.tim.2015.11.008 10.1039/B612394E 10.1093/cid/ciaa210 10.1038/sj.icb.7100007 10.1073/pnas.91.20.9297 10.1038/nrmicro3456 10.1111/j.1365-2958.1991.tb00723.x 10.1007/s10620-017-4535-9 10.1371/journal.pone.0068993 10.2337/db17-0788 10.1038/s41586-018-0344-3 10.1111/j.1600-0765.2010.01277.x 10.2174/0929867324666170425100416 10.2174/1389203053027494 10.3389/fimmu.2018.00679 10.1111/mmi.14565 10.1021/bi800448h 10.3390/jof7040260 10.3389/fcimb.2020.596570 10.1007/s00296-013-2816-y 10.1507/endocrj.EJ14-0471 10.3390/jcm11154496 10.1007/BF02048367 10.1016/j.bbamem.2015.05.012 10.1007/s00018-004-4461-9 10.1038/s41396-022-01240-9 10.1016/j.regpep.2010.01.006 10.1038/srep16643 10.1111/j.1748-1716.2007.01806.x 10.1016/j.chembiol.2020.07.024 10.1111/j.1399-3011.2004.00182.x 10.1172/JCI7394 10.1016/j.tig.2020.03.006 10.1007/s10620-012-2259-4 10.1038/nature12726 10.1016/j.isci.2021.103342 10.3390/jof4030097 10.1016/S0167-0115(00)00135-X 10.1016/j.ijbiomac.2021.04.069 10.1210/en.2008-1613 10.1016/S0140-6736(15)60078-2 10.1080/19490976.2022.2081476 10.1021/ar300265y 10.1074/jbc.M112.407916 10.3390/jof9010117 10.1097/MCG.0b013e3181e5d06b 10.1016/j.bpj.2012.06.004 10.1038/s41598-017-15436-z 10.1074/jbc.274.5.2920 10.1038/s41569-022-00760-3 10.1038/s41574-022-00773-5 10.1111/j.1469-0691.2011.03552.x 10.1007/s11894-018-0636-7 10.1186/1476-0711-11-32 10.1128/MMBR.69.4.585-607.2005 10.1093/femsre/fuaa054 10.1016/S0167-0115(98)00040-8 10.1194/jlr.R036012 10.1021/ja0121639 10.1016/j.jaci.2019.11.003 10.1038/mi.2016.42 10.1016/j.isci.2022.104158 10.3389/fimmu.2017.00985 10.1148/rg.344130134 10.1038/s41598-019-48775-0 10.1177/1753465812443094 10.1093/ibd/izz046 10.3390/microorganisms9030618 10.1097/01.hjh.0000222760.99852.e0 10.3390/nu11081943 10.1053/j.gastro.2011.11.037 10.1038/415389a 10.1074/jbc.M101545200 10.1016/S0022-2836(02)00465-5 10.1016/j.it.2021.11.002 10.1093/jn/137.6.1504S 10.1038/sj.jid.5701225 10.1111/apha.13655 10.1002/pro.655 10.1016/j.idc.2015.10.013 10.1016/j.tim.2021.11.009 10.1016/0306-4522(92)90222-N 10.1016/j.tim.2009.12.004 10.1016/j.ajhg.2020.05.011 10.2174/1389201019666180528094202 10.1146/annurev-micro-091213-112949 10.1126/science.aau5480 10.1097/00004836-200603000-00015 10.1016/j.aca.2022.339696 10.1073/pnas.0909122107 10.1074/jbc.M001232200 10.1016/j.mayocp.2014.12.002 10.1080/01676830.2021.1990351 10.1002/anie.200390319 10.1210/er.2010-0027 10.1210/en.2007-0838 10.1371/journal.pone.0004501 10.1093/mmy/myy086 10.1111/j.1365-2567.2010.03395.x 10.1152/ajpgi.00346.2017 10.1038/nri1956 10.1111/j.1365-2036.2011.04757.x 10.1161/HYPERTENSIONAHA.120.16809 10.1177/0148607197021006357 10.1039/C1MB05239J 10.1038/nature12721 10.1126/sciadv.aaz6333 10.3390/antibiotics9120898 10.1021/ja027200q 10.1016/j.bbamem.2008.08.023 10.1080/22221751.2019.1638734 10.1038/333784a0 10.1016/j.cgh.2011.08.014 10.1128/mBio.02123-20 10.2174/1874091X01004010053 10.1007/BF02704101 10.1128/CMR.00008-07 10.1016/S0167-0115(03)00069-7 10.1021/bi0300433 10.3389/fcimb.2016.00194 10.1080/19490976.2015.1134082 10.1016/j.bbrc.2022.06.069 10.1038/nrendo.2015.128 10.1016/S0196-9781(98)00086-2 10.1016/j.cmi.2018.07.011 10.3390/ijms23042066 10.1172/JCI119686 10.1038/s41598-019-51878-3 10.2174/1568013043357608 10.1063/1.3168393 10.1111/nyas.14249 10.1093/nar/20.12.3113 10.3390/antibiotics9080445 10.1080/1120009X.2017.1380395 10.1021/bi035948v 10.1007/s10620-017-4833-2 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2023 MDPI AG 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2023 by the authors. 2023 |
| Copyright_xml | – notice: COPYRIGHT 2023 MDPI AG – notice: 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2023 by the authors. 2023 |
| DBID | NPM AAYXX CITATION 3V. 7XB 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU COVID DWQXO GNUQQ GUQSH M2O MBDVC PIMPY PQEST PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA |
| DOI | 10.3390/pharmaceutics15051550 |
| DatabaseName | PubMed CrossRef ProQuest Central (Corporate) ProQuest Central (purchase pre-March 2016) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College Coronavirus Research Database ProQuest Central Korea ProQuest Central Student Research Library Prep Research Library Research Library (Corporate) Publicly Available Content Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | PubMed CrossRef Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest Central Basic ProQuest Central Essentials ProQuest One Academic Eastern Edition Coronavirus Research Database ProQuest Central (Alumni Edition) ProQuest One Community College Research Library (Alumni Edition) ProQuest Central China ProQuest Central ProQuest One Academic UKI Edition ProQuest Central Korea ProQuest Research Library ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef Publicly Available Content Database PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: COVID name: Coronavirus Research Database url: https://proxy.k.utb.cz/login?url=https://search.proquest.com/coronavirus sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1999-4923 |
| ExternalDocumentID | oai_doaj_org_article_90ada8faac4f44b193fafbf8ec5d7dd9 A750994100 10_3390_pharmaceutics15051550 37242791 |
| Genre | Journal Article Review |
| GrantInformation_xml | – fundername: NIA NIH HHS grantid: R21 AG072487 – fundername: NIH HHS grantid: 1 R21 AG072487-01 and 1 R21 AG080246-01 to S.K.M. – fundername: NIA NIH HHS grantid: R21 AG080246 – fundername: National Institutes of Health grantid: 1 R21 AG072487-01 – fundername: AFTD Holloway Postdoctoral Fellowship grantid: Award #2020-02 – fundername: National Institutes of Health grantid: 1 R21 AG080246-01 |
| GroupedDBID | --- 3V. 53G 5VS 8G5 AADQD ABDBF ABUWG ACGFO ACIHN AEAQA AFKRA AFZYC ALMA_UNASSIGNED_HOLDINGS AZQEC BENPR BPHCQ CCPQU DIK DWQXO EBD ESX F5P FD6 GNUQQ GROUPED_DOAJ GUQSH GX1 HH5 HYE IAO IHR ITC KQ8 M2O M48 MK0 MODMG M~E NPM OK1 P6G PGMZT PIMPY PQQKQ PROAC RIG RNS RPM TR2 TUS AAYXX CITATION 7XB 8FK COVID MBDVC PQEST PQUKI PRINS Q9U 7X8 5PM |
| ID | FETCH-LOGICAL-c573t-dd6eaa82aebb94509fc38e3b7d7e980f36aa3cc83c074e2e12ebf19f4b4a9dcb3 |
| IEDL.DBID | RPM |
| ISSN | 1999-4923 |
| IngestDate | Fri Oct 04 13:12:58 EDT 2024 Tue Sep 17 21:31:46 EDT 2024 Sat Aug 17 04:42:21 EDT 2024 Thu Oct 10 16:30:39 EDT 2024 Thu Feb 22 23:31:40 EST 2024 Fri Feb 02 04:19:31 EST 2024 Thu Sep 26 17:21:36 EDT 2024 Fri Oct 18 08:44:35 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | catestatin cell permeable peptide Chromogranin A gut microbiome antimicrobial peptide |
| Language | English |
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c573t-dd6eaa82aebb94509fc38e3b7d7e980f36aa3cc83c074e2e12ebf19f4b4a9dcb3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 These authors contributed equally to this work. Dedicated to Marie Helene Metz-Boutigue for establishing catestatin as an antimicrobial and a cell permeable peptide. |
| ORCID | 0000-0003-1649-7149 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220906/ |
| PMID | 37242791 |
| PQID | 2819480803 |
| PQPubID | 2032349 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_90ada8faac4f44b193fafbf8ec5d7dd9 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10220906 proquest_miscellaneous_2820017729 proquest_journals_2819480803 gale_infotracmisc_A750994100 gale_infotracacademiconefile_A750994100 crossref_primary_10_3390_pharmaceutics15051550 pubmed_primary_37242791 |
| PublicationCentury | 2000 |
| PublicationDate | 2023-05-20 |
| PublicationDateYYYYMMDD | 2023-05-20 |
| PublicationDate_xml | – month: 05 year: 2023 text: 2023-05-20 day: 20 |
| PublicationDecade | 2020 |
| PublicationPlace | Switzerland |
| PublicationPlace_xml | – name: Switzerland – name: Basel |
| PublicationTitle | Pharmaceutics |
| PublicationTitleAlternate | Pharmaceutics |
| PublicationYear | 2023 |
| Publisher | MDPI AG MDPI |
| Publisher_xml | – name: MDPI AG – name: MDPI |
| References | ref_91 Mazmanian (ref_95) 2006; 6 Mahapatra (ref_18) 2006; 24 Bhutiani (ref_102) 2018; 20 Rabbi (ref_78) 2016; 7 Dhindsa (ref_147) 2020; 107 Kellis (ref_143) 1988; 333 Cummings (ref_83) 1997; 21 Preece (ref_16) 2004; 118 Rojas (ref_34) 2018; 559 Lee (ref_51) 2012; 11 Mattila (ref_103) 2012; 142 Butler (ref_54) 2011; 17 Grehan (ref_107) 2010; 44 Lee (ref_30) 2015; 1848 Yoshida (ref_94) 2021; 24 Glassner (ref_113) 2020; 145 Kelkar (ref_138) 2006; 31 ref_129 Zhou (ref_111) 2021; 14 Tsuda (ref_124) 2010; 45 Ying (ref_97) 2018; 67 Chen (ref_122) 2019; 25 Zaet (ref_23) 2017; 7 Kennedy (ref_125) 1998; 19 Vasoo (ref_57) 2015; 90 Matta (ref_132) 2003; 9 Dathe (ref_39) 2004; 43 Vollmer (ref_33) 2010; 18 Muntjewerff (ref_99) 2021; 232 Biswas (ref_73) 2012; 60 Livovsky (ref_104) 2018; 63 ref_71 Taylor (ref_7) 2000; 275 Sahu (ref_145) 2012; 287 Tsigelny (ref_38) 1998; 77 Setianingrum (ref_68) 2019; 57 ref_152 McConnell (ref_27) 2021; 45 ref_75 Parmer (ref_8) 2000; 106 ref_74 Muntjewerff (ref_151) 2022; 43 Scavello (ref_44) 2021; 11 Cohen (ref_105) 2017; 62 Schneeberger (ref_110) 2015; 5 Zhao (ref_144) 2011; 20 (ref_80) 2021; 181 (ref_141) 2012; 8 Bakken (ref_108) 2011; 9 Bowdish (ref_36) 2005; 6 Percy (ref_35) 2014; 68 Schwalbe (ref_100) 2022; 16 Wadhwani (ref_31) 2012; 103 Wong (ref_82) 2006; 40 Cunha (ref_49) 2016; 387 Abdulamir (ref_118) 2010; 4 Kroon (ref_65) 2011; 49 Morrison (ref_116) 2016; 7 Zasloff (ref_1) 2002; 415 Blair (ref_56) 2014; 9 Wen (ref_22) 2004; 74 Kojima (ref_127) 2018; 118 Meyer (ref_140) 2003; 42 Furusawa (ref_121) 2013; 504 Mahdavinia (ref_61) 2012; 6 Biswas (ref_12) 2009; 150 Muller (ref_90) 2019; 9 Wang (ref_119) 2012; 57 Kim (ref_48) 2020; 10 Bonten (ref_46) 2021; 72 Wexler (ref_92) 2007; 20 Winslet (ref_106) 1993; 36 Schwalbe (ref_109) 2022; 14 Jati (ref_130) 2018; 9 Briolat (ref_21) 2005; 62 Fregeau (ref_123) 1992; 20 Aung (ref_128) 2011; 132 Loladze (ref_142) 2002; 320 Ying (ref_98) 2021; 77 Pechous (ref_47) 2016; 24 Kruger (ref_126) 2003; 114 Capatina (ref_52) 2022; 1204 Dougherty (ref_134) 2007; 137 Groen (ref_114) 2013; 54 Hennebique (ref_53) 2019; 8 Geboes (ref_117) 2011; 34 Taupenot (ref_14) 2000; 95 Mahata (ref_20) 2018; 25 Radek (ref_24) 2008; 128 Canfora (ref_89) 2015; 11 Salazar (ref_76) 2017; 8 Brunner (ref_150) 2023; 19 Dougherty (ref_135) 2013; 46 Lazzaro (ref_40) 2020; 368 Rees (ref_149) 2020; 36 Reigstad (ref_84) 2015; 29 Mahata (ref_13) 1999; 274 Winkler (ref_2) 1992; 49 Mahata (ref_15) 2000; 14 Sahu (ref_37) 2012; 125 Welch (ref_28) 1991; 5 ref_60 Yang (ref_93) 2017; 10 ref_69 Psichas (ref_87) 2015; 39 Lee (ref_10) 2003; 42 ref_63 ref_62 Vaingankar (ref_3) 2008; 192 Brown (ref_26) 2020; 27 Rabbi (ref_77) 2017; 8 Coburn (ref_50) 2007; 85 Scheffers (ref_25) 2005; 69 Mahata (ref_19) 2010; 162 Bolognini (ref_115) 2016; 89 Choi (ref_146) 2015; 62 Mahata (ref_6) 2019; 1455 Wessolowski (ref_41) 2004; 64 Arpaia (ref_120) 2013; 504 Ge (ref_85) 2018; 19 Brocchieri (ref_139) 1994; 91 Mahata (ref_17) 2004; 4 Bogdanov (ref_32) 2020; 6 McGarrah (ref_148) 2023; 20 Costa (ref_45) 2015; 13 Sizemore (ref_58) 2013; 33 Cristy (ref_72) 2020; 11 Biswas (ref_11) 2008; 149 Scheiner (ref_133) 2002; 124 Jiang (ref_9) 2001; 276 Mazzariol (ref_55) 2017; 29 Earley (ref_112) 2019; 9 Epand (ref_43) 2009; 1788 Bartolomucci (ref_4) 2011; 32 Round (ref_96) 2010; 107 Zhang (ref_131) 2009; 131 Jude (ref_59) 2014; 34 Yajima (ref_137) 2007; 3 Ma (ref_88) 2022; 621 Chelli (ref_136) 2002; 124 Castano (ref_42) 2008; 47 Christiansen (ref_86) 2018; 315 ref_101 Jeong (ref_66) 2019; 25 Mahata (ref_5) 1997; 100 McCarty (ref_64) 2016; 30 Bornet (ref_81) 2022; 30 Mahlapuu (ref_29) 2016; 6 Bermas (ref_70) 2020; 114 Nair (ref_67) 2022; 41 Horvath (ref_79) 2022; 25 |
| References_xml | – volume: 118 start-page: 75 year: 2004 ident: ref_16 article-title: Conformational preferences and activities of peptides from the catecholamine release-inhibitory (catestatin) region of Chromogranin A publication-title: Regul. Pept. doi: 10.1016/j.regpep.2003.10.035 contributor: fullname: Preece – volume: 74 start-page: 197 year: 2004 ident: ref_22 article-title: Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology publication-title: Am. J. Hum. Genet. doi: 10.1086/381399 contributor: fullname: Wen – volume: 118 start-page: 182 year: 2018 ident: ref_127 article-title: Catestatin Prevents Macrophage-Driven Atherosclerosis but Not Arterial Injury-Induced Neointimal Hyperplasia publication-title: Thromb. Haemost. doi: 10.1160/TH17-05-0349 contributor: fullname: Kojima – volume: 9 start-page: 1940 year: 2003 ident: ref_132 article-title: Hydrogen-hydrogen bonding: A stabilizing interaction in molecules and crystals publication-title: Chemistry (Easton) contributor: fullname: Matta – volume: 89 start-page: 388 year: 2016 ident: ref_115 article-title: The Pharmacology and Function of Receptors for Short-Chain Fatty Acids publication-title: Mol. Pharmacol. doi: 10.1124/mol.115.102301 contributor: fullname: Bolognini – volume: 39 start-page: 424 year: 2015 ident: ref_87 article-title: The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents publication-title: Int. J. Obes. (Lond.) doi: 10.1038/ijo.2014.153 contributor: fullname: Psichas – volume: 9 start-page: 1165 year: 2014 ident: ref_56 article-title: Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance publication-title: Future Microbiol. doi: 10.2217/fmb.14.66 contributor: fullname: Blair – volume: 11 start-page: 15615 year: 2021 ident: ref_44 article-title: Catestatin in innate immunity and Cateslytin-derived peptides against superbugs publication-title: Sci. Rep. doi: 10.1038/s41598-021-94749-6 contributor: fullname: Scavello – volume: 29 start-page: 1395 year: 2015 ident: ref_84 article-title: Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells publication-title: FASEB J. doi: 10.1096/fj.14-259598 contributor: fullname: Reigstad – volume: 14 start-page: 2177 year: 2021 ident: ref_111 article-title: Association Between Gut Akkermansia and Metabolic Syndrome is Dose-Dependent and Affected by Microbial Interactions: A Cross-Sectional Study publication-title: Diabetes Metab. Syndr. Obes. doi: 10.2147/DMSO.S311388 contributor: fullname: Zhou – volume: 125 start-page: 2323 year: 2012 ident: ref_37 article-title: Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor publication-title: J. Cell Sci. doi: 10.1242/jcs.114389 contributor: fullname: Sahu – volume: 60 start-page: 1552 year: 2012 ident: ref_73 article-title: Novel peptide isomer strategy for stable inhibition of catecholamine release: Application to hypertension publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.112.202127 contributor: fullname: Biswas – volume: 24 start-page: 190 year: 2016 ident: ref_47 article-title: Pneumonic Plague: The Darker Side of Yersinia pestis publication-title: Trends Microbiol. doi: 10.1016/j.tim.2015.11.008 contributor: fullname: Pechous – volume: 3 start-page: 299 year: 2007 ident: ref_137 article-title: π-π stacking assisted binding of aromatic amino acids by copper(II)-aromatic diimine complexes. Effects of ring substituents on ternary complex stability publication-title: Dalton Trans. doi: 10.1039/B612394E contributor: fullname: Yajima – volume: 72 start-page: 1211 year: 2021 ident: ref_46 article-title: Epidemiology of Escherichia coli Bacteremia: A Systematic Literature Review publication-title: Clin. Infect. Dis. doi: 10.1093/cid/ciaa210 contributor: fullname: Bonten – volume: 85 start-page: 112 year: 2007 ident: ref_50 article-title: Salmonella, the host and disease: A brief review publication-title: Immunol. Cell Biol. doi: 10.1038/sj.icb.7100007 contributor: fullname: Coburn – volume: 91 start-page: 9297 year: 1994 ident: ref_139 article-title: Geometry of interplanar residue contacts in protein structures publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.91.20.9297 contributor: fullname: Brocchieri – volume: 13 start-page: 343 year: 2015 ident: ref_45 article-title: Secretion systems in Gram-negative bacteria: Structural and mechanistic insights publication-title: Nat. Rev. Microbiol. doi: 10.1038/nrmicro3456 contributor: fullname: Costa – volume: 5 start-page: 521 year: 1991 ident: ref_28 article-title: Pore-forming cytolysins of gram-negative bacteria publication-title: Mol. Microbiol. doi: 10.1111/j.1365-2958.1991.tb00723.x contributor: fullname: Welch – volume: 62 start-page: 1131 year: 2017 ident: ref_105 article-title: Novel Indications for Fecal Microbial Transplantation: Update and Review of the Literature publication-title: Dig. Dis. Sci. doi: 10.1007/s10620-017-4535-9 contributor: fullname: Cohen – ident: ref_74 doi: 10.1371/journal.pone.0068993 – volume: 67 start-page: 841 year: 2018 ident: ref_97 article-title: Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production, Leading to Improved Insulin Sensitivity publication-title: Diabetes doi: 10.2337/db17-0788 contributor: fullname: Ying – volume: 559 start-page: 617 year: 2018 ident: ref_34 article-title: The outer membrane is an essential load-bearing element in Gram-negative bacteria publication-title: Nature doi: 10.1038/s41586-018-0344-3 contributor: fullname: Rojas – volume: 45 start-page: 626 year: 2010 ident: ref_124 article-title: Butyrate, a bacterial metabolite, induces apoptosis and autophagic cell death in gingival epithelial cells publication-title: J. Periodontal Res. doi: 10.1111/j.1600-0765.2010.01277.x contributor: fullname: Tsuda – volume: 25 start-page: 1352 year: 2018 ident: ref_20 article-title: Catestatin: A Master Regulator of Cardiovascular Functions publication-title: Curr. Med. Chem. doi: 10.2174/0929867324666170425100416 contributor: fullname: Mahata – volume: 6 start-page: 35 year: 2005 ident: ref_36 article-title: A re-evaluation of the role of host defence peptides in mammalian immunity publication-title: Curr. Protein. Pept. Sci. doi: 10.2174/1389203053027494 contributor: fullname: Bowdish – volume: 9 start-page: 679 year: 2018 ident: ref_130 article-title: Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit publication-title: Front. Immunol. doi: 10.3389/fimmu.2018.00679 contributor: fullname: Jati – volume: 114 start-page: 721 year: 2020 ident: ref_70 article-title: Combatting the evolution of antifungal resistance in Cryptococcus neoformans publication-title: Mol. Microbiol. doi: 10.1111/mmi.14565 contributor: fullname: Bermas – volume: 47 start-page: 6394 year: 2008 ident: ref_42 article-title: Aggregation of cateslytin beta-sheets on negatively charged lipids promotes rigid membrane domains. A new mode of action for antimicrobial peptides? publication-title: Biochemistry doi: 10.1021/bi800448h contributor: fullname: Castano – ident: ref_69 doi: 10.3390/jof7040260 – volume: 7 start-page: 2151 year: 2016 ident: ref_78 article-title: Human Catestatin Alters Gut Microbiota Composition in Mice publication-title: Front. Microbiol. contributor: fullname: Rabbi – volume: 10 start-page: 596570 year: 2020 ident: ref_48 article-title: Review on Stress Tolerance in Campylobacter jejuni publication-title: Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2020.596570 contributor: fullname: Kim – volume: 33 start-page: 2963 year: 2013 ident: ref_58 article-title: Rheumatologic manifestations of histoplasmosis: A review publication-title: Rheumatol. Int. doi: 10.1007/s00296-013-2816-y contributor: fullname: Sizemore – volume: 62 start-page: 797 year: 2015 ident: ref_146 article-title: A common genetic variant of the Chromogranin A-derived peptide catestatin is associated with atherogenesis and hypertension in a Japanese population publication-title: Endocr. J. doi: 10.1507/endocrj.EJ14-0471 contributor: fullname: Choi – ident: ref_129 doi: 10.3390/jcm11154496 – volume: 36 start-page: 757 year: 1993 ident: ref_106 article-title: Fecal diversion in the management of Crohn’s disease of the colon publication-title: Dis. Colon Rectum doi: 10.1007/BF02048367 contributor: fullname: Winslet – volume: 1848 start-page: 1868 year: 2015 ident: ref_30 article-title: New insights into the molecular mechanisms of biomembrane structural changes and interactions by optical biosensor technology publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbamem.2015.05.012 contributor: fullname: Lee – volume: 62 start-page: 377 year: 2005 ident: ref_21 article-title: New antimicrobial activity for the catecholamine release-inhibitory peptide from Chromogranin A publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-004-4461-9 contributor: fullname: Briolat – volume: 16 start-page: 1873 year: 2022 ident: ref_100 article-title: Catestatin selects for colonization of antimicrobial-resistant gut bacterial communities publication-title: ISME J. doi: 10.1038/s41396-022-01240-9 contributor: fullname: Schwalbe – volume: 162 start-page: 33 year: 2010 ident: ref_19 article-title: Catestatin: A multifunctional peptide from Chromogranin A publication-title: Regul. Pept. doi: 10.1016/j.regpep.2010.01.006 contributor: fullname: Mahata – volume: 5 start-page: 16643 year: 2015 ident: ref_110 article-title: Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice publication-title: Sci. Rep. doi: 10.1038/srep16643 contributor: fullname: Schneeberger – volume: 192 start-page: 309 year: 2008 ident: ref_3 article-title: Chromogranins A and B and secretogranin II: Evolutionary and functional aspects publication-title: Acta Physiol. (Oxf.) doi: 10.1111/j.1748-1716.2007.01806.x contributor: fullname: Vaingankar – volume: 27 start-page: 1052 year: 2020 ident: ref_26 article-title: Chemical Biology Tools for Examining the Bacterial Cell Wall publication-title: Cell. Chem. Biol. doi: 10.1016/j.chembiol.2020.07.024 contributor: fullname: Brown – volume: 64 start-page: 159 year: 2004 ident: ref_41 article-title: Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: The effects of aromatic clusters, D-amino acid substitution and cyclization publication-title: J. Pept. Res. doi: 10.1111/j.1399-3011.2004.00182.x contributor: fullname: Wessolowski – volume: 106 start-page: 907 year: 2000 ident: ref_8 article-title: Processing of Chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion publication-title: J. Clin. Investig. doi: 10.1172/JCI7394 contributor: fullname: Parmer – volume: 36 start-page: 415 year: 2020 ident: ref_149 article-title: The Genomics of Human Local Adaptation publication-title: Trends Genet. doi: 10.1016/j.tig.2020.03.006 contributor: fullname: Rees – volume: 57 start-page: 3126 year: 2012 ident: ref_119 article-title: Butyrate enhances intestinal epithelial barrier function via up-regulation of tight junction protein Claudin-1 transcription publication-title: Dig. Dis. Sci. doi: 10.1007/s10620-012-2259-4 contributor: fullname: Wang – volume: 504 start-page: 451 year: 2013 ident: ref_120 article-title: Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation publication-title: Nature doi: 10.1038/nature12726 contributor: fullname: Arpaia – volume: 24 start-page: 103342 year: 2021 ident: ref_94 article-title: Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity publication-title: iScience doi: 10.1016/j.isci.2021.103342 contributor: fullname: Yoshida – ident: ref_63 doi: 10.3390/jof4030097 – volume: 95 start-page: 9 year: 2000 ident: ref_14 article-title: Interaction of the catecholamine release-inhibitory peptide catestatin (human Chromogranin A(352–372)) with the chromaffin cell surface and Torpedo electroplax: Implications for nicotinic cholinergic antagonism publication-title: Regul. Pept. doi: 10.1016/S0167-0115(00)00135-X contributor: fullname: Taupenot – volume: 181 start-page: 877 year: 2021 ident: ref_80 article-title: A comprehensive review on the impact of beta-glucan metabolism by Bacteroides and Bifidobacterium species as members of the gut microbiota publication-title: Int. J. Biol. Macromol. doi: 10.1016/j.ijbiomac.2021.04.069 – volume: 150 start-page: 3547 year: 2009 ident: ref_12 article-title: Cathepsin L Co-Localizes with Chromogranin A in Chromaffin Vesicles to Generate Active Peptides publication-title: Endocrinology doi: 10.1210/en.2008-1613 contributor: fullname: Biswas – volume: 387 start-page: 376 year: 2016 ident: ref_49 article-title: Legionnaires’ disease publication-title: Lancet doi: 10.1016/S0140-6736(15)60078-2 contributor: fullname: Cunha – volume: 14 start-page: 2081476 year: 2022 ident: ref_109 article-title: Gut microbiota transplantation drives the adoptive transfer of colonic genotype-phenotype characteristics between mice lacking catestatin and their wild type counterparts publication-title: Gut Microbes doi: 10.1080/19490976.2022.2081476 contributor: fullname: Schwalbe – volume: 46 start-page: 885 year: 2013 ident: ref_135 article-title: The cation-pi interaction publication-title: Acc. Chem. Res. doi: 10.1021/ar300265y contributor: fullname: Dougherty – volume: 287 start-page: 43840 year: 2012 ident: ref_145 article-title: Functional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: Allele-specific effects on metabolic traits publication-title: J. Biol. Chem. doi: 10.1074/jbc.M112.407916 contributor: fullname: Sahu – ident: ref_60 doi: 10.3390/jof9010117 – volume: 44 start-page: 551 year: 2010 ident: ref_107 article-title: Durable alteration of the colonic microbiota by the administration of donor fecal flora publication-title: J. Clin. Gastroenterol. doi: 10.1097/MCG.0b013e3181e5d06b contributor: fullname: Grehan – volume: 103 start-page: 265 year: 2012 ident: ref_31 article-title: Membrane-active peptides and the clustering of anionic lipids publication-title: Biophys. J. doi: 10.1016/j.bpj.2012.06.004 contributor: fullname: Wadhwani – volume: 7 start-page: 15199 year: 2017 ident: ref_23 article-title: D-Cateslytin, a new antimicrobial peptide with therapeutic potential publication-title: Sci. Rep. doi: 10.1038/s41598-017-15436-z contributor: fullname: Zaet – volume: 274 start-page: 2920 year: 1999 ident: ref_13 article-title: Desensitization of catecholamine release: The novel catecholamine release-inhibitory peptide catestatin (Chromogranin A344–364) acts at the receptor to prevent nicotinic cholinergic tolerance publication-title: J. Biol. Chem. doi: 10.1074/jbc.274.5.2920 contributor: fullname: Mahata – volume: 20 start-page: 77 year: 2023 ident: ref_148 article-title: Branched-chain amino acids in cardiovascular disease publication-title: Nat. Rev. Cardiol. doi: 10.1038/s41569-022-00760-3 contributor: fullname: McGarrah – volume: 19 start-page: 134 year: 2023 ident: ref_150 article-title: Metabolic determinants of tumour initiation publication-title: Nat. Rev. Endocrinol. doi: 10.1038/s41574-022-00773-5 contributor: fullname: Brunner – volume: 17 start-page: 959 year: 2011 ident: ref_54 article-title: Treatment of typhoid fever in the 21st century: Promises and shortcomings publication-title: Clin. Microbiol. Infect. doi: 10.1111/j.1469-0691.2011.03552.x contributor: fullname: Butler – volume: 20 start-page: 30 year: 2018 ident: ref_102 article-title: Technical Aspects of Fecal Microbial Transplantation (FMT) publication-title: Curr. Gastroenterol. Rep. doi: 10.1007/s11894-018-0636-7 contributor: fullname: Bhutiani – volume: 11 start-page: 32 year: 2012 ident: ref_51 article-title: Treatment of Klebsiella pneumoniae carbapenemase (KPC) infections: A review of published case series and case reports publication-title: Ann. Clin. Microbiol. Antimicrob. doi: 10.1186/1476-0711-11-32 contributor: fullname: Lee – volume: 69 start-page: 585 year: 2005 ident: ref_25 article-title: Bacterial cell wall synthesis: New insights from localization studies publication-title: Microbiol. Mol. Biol. Rev. doi: 10.1128/MMBR.69.4.585-607.2005 contributor: fullname: Scheffers – volume: 45 start-page: fuaa054 year: 2021 ident: ref_27 article-title: Vaccines for multidrug resistant Gram negative bacteria: Lessons from the past for guiding future success publication-title: FEMS Microbiol. Rev. doi: 10.1093/femsre/fuaa054 contributor: fullname: McConnell – volume: 77 start-page: 43 year: 1998 ident: ref_38 article-title: Mechanism of action of Chromogranin A on catecholamine release: Molecular modeling of the catestatin region reveals a b-strand/loop/b-strand structure secured by hydrophobic interactions and predictive of activity publication-title: Regul. Pept. doi: 10.1016/S0167-0115(98)00040-8 contributor: fullname: Tsigelny – volume: 54 start-page: 2325 year: 2013 ident: ref_114 article-title: The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism publication-title: J. Lipid Res. doi: 10.1194/jlr.R036012 contributor: fullname: Groen – volume: 124 start-page: 6133 year: 2002 ident: ref_136 article-title: Stacking and T-shape competition in aromatic-aromatic amino acid interactions publication-title: J. Am. Chem. Soc. doi: 10.1021/ja0121639 contributor: fullname: Chelli – volume: 145 start-page: 16 year: 2020 ident: ref_113 article-title: The microbiome and inflammatory bowel disease publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2019.11.003 contributor: fullname: Glassner – volume: 10 start-page: 104 year: 2017 ident: ref_93 article-title: Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice publication-title: Mucosal Immunol. doi: 10.1038/mi.2016.42 contributor: fullname: Yang – volume: 25 start-page: 104158 year: 2022 ident: ref_79 article-title: Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters publication-title: iScience doi: 10.1016/j.isci.2022.104158 contributor: fullname: Horvath – volume: 8 start-page: 985 year: 2017 ident: ref_77 article-title: Reactivation of Intestinal Inflammation Is Suppressed by Catestatin in a Murine Model of Colitis via M1 Macrophages and Not the Gut Microbiota publication-title: Front. Immunol. doi: 10.3389/fimmu.2017.00985 contributor: fullname: Rabbi – volume: 34 start-page: 912 year: 2014 ident: ref_59 article-title: Pulmonary coccidioidomycosis: Pictorial review of chest radiographic and CT findings publication-title: Radiographics doi: 10.1148/rg.344130134 contributor: fullname: Jude – volume: 9 start-page: 12515 year: 2019 ident: ref_90 article-title: Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans publication-title: Sci. Rep. doi: 10.1038/s41598-019-48775-0 contributor: fullname: Muller – volume: 6 start-page: 173 year: 2012 ident: ref_61 article-title: Management of allergic bronchopulmonary aspergillosis: A review and update publication-title: Ther. Adv. Respir. Dis. doi: 10.1177/1753465812443094 contributor: fullname: Mahdavinia – volume: 25 start-page: 1450 year: 2019 ident: ref_122 article-title: Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells’ Differentiation and Function in Induction of Colitis publication-title: Inflamm. Bowel. Dis. doi: 10.1093/ibd/izz046 contributor: fullname: Chen – ident: ref_101 doi: 10.3390/microorganisms9030618 – volume: 24 start-page: 895 year: 2006 ident: ref_18 article-title: The Chromogranin A fragment catestatin: Specificity, potency and mechanism to inhibit exocytotic secretion of multiple catecholamine storage vesicle co-transmitters publication-title: J. Hypertens. doi: 10.1097/01.hjh.0000222760.99852.e0 contributor: fullname: Mahapatra – ident: ref_91 doi: 10.3390/nu11081943 – volume: 142 start-page: 490 year: 2012 ident: ref_103 article-title: Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infection publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.11.037 contributor: fullname: Mattila – volume: 415 start-page: 389 year: 2002 ident: ref_1 article-title: Antimicrobial peptides of multicellular organisms publication-title: Nature doi: 10.1038/415389a contributor: fullname: Zasloff – volume: 276 start-page: 25022 year: 2001 ident: ref_9 article-title: Proteolytic cleavage of Chromogranin A (CgA) by plasmin: Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release publication-title: J. Biol. Chem. doi: 10.1074/jbc.M101545200 contributor: fullname: Jiang – volume: 320 start-page: 343 year: 2002 ident: ref_142 article-title: Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior publication-title: J. Mol. Biol. doi: 10.1016/S0022-2836(02)00465-5 contributor: fullname: Loladze – volume: 43 start-page: 41 year: 2022 ident: ref_151 article-title: Putative regulation of macrophage-mediated inflammation by catestatin publication-title: Trends Immunol. doi: 10.1016/j.it.2021.11.002 contributor: fullname: Muntjewerff – volume: 137 start-page: 1504S year: 2007 ident: ref_134 article-title: Cation-pi interactions involving aromatic amino acids publication-title: J. Nutr. doi: 10.1093/jn/137.6.1504S contributor: fullname: Dougherty – volume: 128 start-page: 1525 year: 2008 ident: ref_24 article-title: The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury publication-title: J. Investig. Dermatol. doi: 10.1038/sj.jid.5701225 contributor: fullname: Radek – volume: 232 start-page: e13655 year: 2021 ident: ref_99 article-title: Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides publication-title: Acta Physiol. (Oxf.) doi: 10.1111/apha.13655 contributor: fullname: Muntjewerff – volume: 20 start-page: 1275 year: 2011 ident: ref_144 article-title: Charged residues at protein interaction interfaces: Unexpected conservation and orchestrated divergence publication-title: Protein Sci. doi: 10.1002/pro.655 contributor: fullname: Zhao – volume: 30 start-page: 103 year: 2016 ident: ref_64 article-title: Invasive Candidiasis publication-title: Infect. Dis. Clin. N. Am. doi: 10.1016/j.idc.2015.10.013 contributor: fullname: McCarty – volume: 30 start-page: 104 year: 2022 ident: ref_81 article-title: The ambivalent role of Bacteroides in enteric infections publication-title: Trends Microbiol. doi: 10.1016/j.tim.2021.11.009 contributor: fullname: Bornet – volume: 49 start-page: 497 year: 1992 ident: ref_2 article-title: The Chromogranins A and B: The first 25 years and future perspectives publication-title: Neuroscience doi: 10.1016/0306-4522(92)90222-N contributor: fullname: Winkler – volume: 18 start-page: 59 year: 2010 ident: ref_33 article-title: Architecture of peptidoglycan: More data and more models publication-title: Trends Microbiol. doi: 10.1016/j.tim.2009.12.004 contributor: fullname: Vollmer – volume: 107 start-page: 83 year: 2020 ident: ref_147 article-title: Natural Selection Shapes Codon Usage in the Human Genome publication-title: Am. J. Hum. Genet. doi: 10.1016/j.ajhg.2020.05.011 contributor: fullname: Dhindsa – volume: 19 start-page: 190 year: 2018 ident: ref_85 article-title: Intestinal Crosstalk between Microbiota and Serotonin and its Impact on Gut Motility publication-title: Curr. Pharm. Biotechnol. doi: 10.2174/1389201019666180528094202 contributor: fullname: Ge – volume: 49 start-page: 673 year: 2011 ident: ref_65 article-title: Outbreaks and clustering of Pneumocystis pneumonia in kidney transplant recipients: A systematic review publication-title: Med. Mycol. contributor: fullname: Kroon – volume: 68 start-page: 81 year: 2014 ident: ref_35 article-title: Lipoteichoic acid synthesis and function in gram-positive bacteria publication-title: Annu. Rev. Microbiol. doi: 10.1146/annurev-micro-091213-112949 contributor: fullname: Percy – volume: 368 start-page: eaau5480 year: 2020 ident: ref_40 article-title: Antimicrobial peptides: Application informed by evolution publication-title: Science doi: 10.1126/science.aau5480 contributor: fullname: Lazzaro – volume: 40 start-page: 235 year: 2006 ident: ref_82 article-title: Colonic health: Fermentation and short chain fatty acids publication-title: J. Clin. Gastroenterol. doi: 10.1097/00004836-200603000-00015 contributor: fullname: Wong – volume: 1204 start-page: 339696 year: 2022 ident: ref_52 article-title: Analytical methods for the characterization and diagnosis of infection with Pseudomonas aeruginosa: A critical review publication-title: Anal. Chim. Acta doi: 10.1016/j.aca.2022.339696 contributor: fullname: Capatina – volume: 107 start-page: 12204 year: 2010 ident: ref_96 article-title: Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0909122107 contributor: fullname: Round – volume: 275 start-page: 22905 year: 2000 ident: ref_7 article-title: Formation of the catecholamine release-inhibitory peptide catestatin from Chromogranin A. Determination of proteolytic cleavage sites in hormone storage granules publication-title: J. Biol. Chem. doi: 10.1074/jbc.M001232200 contributor: fullname: Taylor – volume: 90 start-page: 395 year: 2015 ident: ref_57 article-title: Emerging issues in gram-negative bacterial resistance: An update for the practicing clinician publication-title: Mayo Clin. Proc. doi: 10.1016/j.mayocp.2014.12.002 contributor: fullname: Vasoo – volume: 41 start-page: 275 year: 2022 ident: ref_67 article-title: Transcutaneous retrobulbar injection of amphotericin B in rhino-orbital-cerebral mucormycosis: A review publication-title: Orbit doi: 10.1080/01676830.2021.1990351 contributor: fullname: Nair – volume: 42 start-page: 1210 year: 2003 ident: ref_140 article-title: Interactions with aromatic rings in chemical and biological recognition publication-title: Angew. Chem. Int. Ed. Engl. doi: 10.1002/anie.200390319 contributor: fullname: Meyer – volume: 32 start-page: 755 year: 2011 ident: ref_4 article-title: The extended granin family: Structure, function, and biomedical implications publication-title: Endocr. Rev. doi: 10.1210/er.2010-0027 contributor: fullname: Bartolomucci – volume: 149 start-page: 749 year: 2008 ident: ref_11 article-title: Proteolytic cleavage of human Chromogranin A containing naturally occurring catestatin variants: Differential processing at catestatin region by plasmin publication-title: Endocrinology doi: 10.1210/en.2007-0838 contributor: fullname: Biswas – ident: ref_152 doi: 10.1371/journal.pone.0004501 – volume: 57 start-page: 133 year: 2019 ident: ref_68 article-title: Pulmonary cryptococcosis: A review of pathobiology and clinical aspects publication-title: Med. Mycol. doi: 10.1093/mmy/myy086 contributor: fullname: Setianingrum – volume: 132 start-page: 527 year: 2011 ident: ref_128 article-title: Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines publication-title: Immunology doi: 10.1111/j.1365-2567.2010.03395.x contributor: fullname: Aung – volume: 315 start-page: G53 year: 2018 ident: ref_86 article-title: The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00346.2017 contributor: fullname: Christiansen – volume: 6 start-page: 849 year: 2006 ident: ref_95 article-title: The love-hate relationship between bacterial polysaccharides and the host immune system publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1956 contributor: fullname: Mazmanian – volume: 34 start-page: 526 year: 2011 ident: ref_117 article-title: Kinetics of butyrate metabolism in the normal colon and in ulcerative colitis: The effects of substrate concentration and carnitine on the beta-oxidation pathway publication-title: Aliment. Pharmacol. Ther. doi: 10.1111/j.1365-2036.2011.04757.x contributor: fullname: Geboes – volume: 77 start-page: 1670 year: 2021 ident: ref_98 article-title: Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin) publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.120.16809 contributor: fullname: Ying – volume: 21 start-page: 357 year: 1997 ident: ref_83 article-title: Role of intestinal bacteria in nutrient metabolism publication-title: JPEN J. Parenter. Enteral Nutr. doi: 10.1177/0148607197021006357 contributor: fullname: Cummings – volume: 8 start-page: 237 year: 2012 ident: ref_141 article-title: Aromatic residues link binding and function of intrinsically disordered proteins publication-title: Mol. Biosyst. doi: 10.1039/C1MB05239J – volume: 504 start-page: 446 year: 2013 ident: ref_121 article-title: Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells publication-title: Nature doi: 10.1038/nature12721 contributor: fullname: Furusawa – volume: 6 start-page: eaaz6333 year: 2020 ident: ref_32 article-title: Phospholipid distribution in the cytoplasmic membrane of Gram-negative bacteria is highly asymmetric, dynamic, and cell shape-dependent publication-title: Sci. Adv. doi: 10.1126/sciadv.aaz6333 contributor: fullname: Bogdanov – ident: ref_62 doi: 10.3390/antibiotics9120898 – volume: 124 start-page: 13257 year: 2002 ident: ref_133 article-title: Comparison of various types of hydrogen bonds involving aromatic amino acids publication-title: J. Am. Chem. Soc. doi: 10.1021/ja027200q contributor: fullname: Scheiner – volume: 1788 start-page: 289 year: 2009 ident: ref_43 article-title: Lipid domains in bacterial membranes and the action of antimicrobial agents publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbamem.2008.08.023 contributor: fullname: Epand – volume: 8 start-page: 1027 year: 2019 ident: ref_53 article-title: Tularemia as a waterborne disease: A review publication-title: Emerg. Microbes Infect. doi: 10.1080/22221751.2019.1638734 contributor: fullname: Hennebique – volume: 333 start-page: 784 year: 1988 ident: ref_143 article-title: Contribution of hydrophobic interactions to protein stability publication-title: Nature doi: 10.1038/333784a0 contributor: fullname: Kellis – volume: 9 start-page: 1044 year: 2011 ident: ref_108 article-title: Treating Clostridium difficile infection with fecal microbiota transplantation publication-title: Clin. Gastroenterol. Hepatol. doi: 10.1016/j.cgh.2011.08.014 contributor: fullname: Bakken – volume: 11 start-page: e02123-20 year: 2020 ident: ref_72 article-title: Antimicrobial Peptides: A New Frontier in Antifungal Therapy publication-title: mBio doi: 10.1128/mBio.02123-20 contributor: fullname: Cristy – volume: 4 start-page: 53 year: 2010 ident: ref_118 article-title: The impact of the level of the intestinal short chain Fatty acids in inflammatory bowel disease patients versus healthy subjects publication-title: Open Biochem. J. doi: 10.2174/1874091X01004010053 contributor: fullname: Abdulamir – volume: 14 start-page: 1525 year: 2000 ident: ref_15 article-title: Primary structure and function of the catecholamine release inhibitory peptide catestatin (Chromogranin A344–364): Identification of amino acid residues crucial for activity publication-title: Mol. Endocrinol. contributor: fullname: Mahata – volume: 31 start-page: 297 year: 2006 ident: ref_138 article-title: Membrane interfacial localization of aromatic amino acids and membrane protein function publication-title: J. Biosci. doi: 10.1007/BF02704101 contributor: fullname: Kelkar – volume: 20 start-page: 593 year: 2007 ident: ref_92 article-title: Bacteroides: The good, the bad, and the nitty-gritty publication-title: Clin. Microbiol. Rev. doi: 10.1128/CMR.00008-07 contributor: fullname: Wexler – volume: 114 start-page: 29 year: 2003 ident: ref_126 article-title: Catestatin (CgA344–364) stimulates rat mast cell release of histamine in a manner comparable to mastoparan and other cationic charged neuropeptides publication-title: Regul. Pept. doi: 10.1016/S0167-0115(03)00069-7 contributor: fullname: Kruger – volume: 8 start-page: 376 year: 2017 ident: ref_76 article-title: Shaping the Metabolism of Intestinal Bacteroides Population through Diet to Improve Human Health publication-title: Front. Microbiol. contributor: fullname: Salazar – volume: 42 start-page: 6938 year: 2003 ident: ref_10 article-title: Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting Chromogranin A into active catestatin secreted from neuroendocrine chromaffin cells publication-title: Biochemistry doi: 10.1021/bi0300433 contributor: fullname: Lee – volume: 6 start-page: 194 year: 2016 ident: ref_29 article-title: Antimicrobial Peptides: An Emerging Category of Therapeutic Agents publication-title: Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2016.00194 contributor: fullname: Mahlapuu – volume: 7 start-page: 189 year: 2016 ident: ref_116 article-title: Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism publication-title: Gut Microbes doi: 10.1080/19490976.2015.1134082 contributor: fullname: Morrison – volume: 621 start-page: 176 year: 2022 ident: ref_88 article-title: Phloretin suppresses carbohydrate-induced GLP-1 secretion via inhibiting short chain fatty acid release from gut microbiome publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2022.06.069 contributor: fullname: Ma – volume: 11 start-page: 577 year: 2015 ident: ref_89 article-title: Short-chain fatty acids in control of body weight and insulin sensitivity publication-title: Nat. Rev. Endocrinol. doi: 10.1038/nrendo.2015.128 contributor: fullname: Canfora – volume: 19 start-page: 1241 year: 1998 ident: ref_125 article-title: Mechanism of cardiovascular actions of the Chromogranin A fragment catestatin in vivo publication-title: Peptides doi: 10.1016/S0196-9781(98)00086-2 contributor: fullname: Kennedy – volume: 25 start-page: 26 year: 2019 ident: ref_66 article-title: The epidemiology and clinical manifestations of mucormycosis: A systematic review and meta-analysis of case reports publication-title: Clin. Microbiol. Infect. doi: 10.1016/j.cmi.2018.07.011 contributor: fullname: Jeong – ident: ref_75 doi: 10.3390/ijms23042066 – volume: 100 start-page: 1623 year: 1997 ident: ref_5 article-title: Novel autocrine feedback control of catecholamine release. A discrete Chromogranin A fragment is a noncompetitive nicotinic cholinergic antagonist publication-title: J. Clin. Investig. doi: 10.1172/JCI119686 contributor: fullname: Mahata – volume: 9 start-page: 15683 year: 2019 ident: ref_112 article-title: The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis publication-title: Sci. Rep. doi: 10.1038/s41598-019-51878-3 contributor: fullname: Earley – volume: 4 start-page: 221 year: 2004 ident: ref_17 article-title: Catestatin—The catecholamine release inhibitory peptide: A structural and functional overview publication-title: Curr. Med. Chem. Immun. Endoc. Metab. Agents doi: 10.2174/1568013043357608 contributor: fullname: Mahata – volume: 131 start-page: 035103 year: 2009 ident: ref_131 article-title: Electronic structure of aromatic amino acids studied by soft x-ray spectroscopy publication-title: J. Chem. Phys. doi: 10.1063/1.3168393 contributor: fullname: Zhang – volume: 1455 start-page: 34 year: 2019 ident: ref_6 article-title: Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation publication-title: Ann. N. Y. Acad. Sci. doi: 10.1111/nyas.14249 contributor: fullname: Mahata – volume: 20 start-page: 3113 year: 1992 ident: ref_123 article-title: Two cytotoxic cell proteinase genes are differentially sensitive to sodium butyrate publication-title: Nucleic Acids Res. doi: 10.1093/nar/20.12.3113 contributor: fullname: Fregeau – ident: ref_71 doi: 10.3390/antibiotics9080445 – volume: 29 start-page: 2 year: 2017 ident: ref_55 article-title: Multi-drug-resistant Gram-negative bacteria causing urinary tract infections: A review publication-title: J. Chemother. doi: 10.1080/1120009X.2017.1380395 contributor: fullname: Mazzariol – volume: 43 start-page: 9140 year: 2004 ident: ref_39 article-title: Cyclization increases the antimicrobial activity and selectivity of arginine- and tryptophan-containing hexapeptides publication-title: Biochemistry doi: 10.1021/bi035948v contributor: fullname: Dathe – volume: 63 start-page: 198 year: 2018 ident: ref_104 article-title: Fecal Transplantation for Treatment of Clostridium Difficile Infection in Elderly and Debilitated Patients publication-title: Dig. Dis. Sci. doi: 10.1007/s10620-017-4833-2 contributor: fullname: Livovsky |
| SSID | ssj0000331839 |
| Score | 2.3576035 |
| SecondaryResourceType | review_article |
| Snippet | The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health... |
| SourceID | doaj pubmedcentral proquest gale crossref pubmed |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database |
| StartPage | 1550 |
| SubjectTerms | Amino acids Antibacterial agents Antibiotics Antimicrobial agents antimicrobial peptide Bacteria Bacterial infections Catecholamines catestatin cell permeable peptide Cholera Chromogranin A Drug resistance E coli Fungal infections Fungi Gram-negative bacteria Gram-positive bacteria gut microbiome Membranes Peptides Review Salmonella Tropical diseases |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQT1wQbwIFBQmVS0Md20lsDkhLxapCAu2hlXqzPH6oeyBbddND_z0zSbqbCCQuXG3HjxmP_U08_szYB9E4LsDXhQBwhXLAC0DcXgSjKl2X2ruebf_Hz_rsQn2_rC4nT31RTNhADzwI7sRwF5xOznmVlALEG8klSDr6KjQhDFf3ymriTPVrsKS5aoYrOxL9-pPrq_0v4i2iIHrahM82o56z_8-VebI1zcMmJ_vQ8jF7NALIfDF0_Al7ENun7Gg1tHt3nJ_vL1Rtj_OjfLXnpr57xr6cErak4_f2c75ou_Wvdc_EhDUucYfrJ2Hu2pCvNh3FEWH6tMLn7GL57fz0rBifUCh81ciuCKGOzmnhIgBKn5vkpY4SmtBEo3mStXPSey09QokoYikipNIkBcqZ4EG-YAftpo2vWC6TT8mXgBYvlDfRKOK-M7EEoogHnrFP97K01wNThkUPg4Rv_yr8jH0lie8KE9F1n4Dqt6P67b_Un7GPpC9L5ohK8W68VYB9JmIruyBEZFTJsbnDWUk0Iz_Pvte4Hc14a-mUURHzpszY-102fUmhaW3c3FIZCksjJyVjL4cJshuSbBABNabMmJ5NndmY5znt-qon-SZPnBtev_4fUnrDHgoEZxT1IPghO-hubuNbBFMdvOvt5jeZgSQZ priority: 102 providerName: Directory of Open Access Journals – databaseName: Coronavirus Research Database dbid: COVID link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB7B9sKFNzRQUJBQuTRbJ_YmNgfQsrAqSMAeWtSb5SddIZKlmz2UX48nyT4CiANX23E8mvH4G3v8GeB5ViiSaZMnmdYqYUqTRAfcnljBRjxPuVEN2_7HT_nJGftwPjrvNtyWXVrl2ic2jtpWBvfIj_HAhyEJIn29-JHgq1F4uto9oXEd9igPkc4A9iafv7x_u9llIRRtVrRXd2iI748XF9ut4mVAQ_jECektSg13_58eemeJ6qdP7qxH01sg15K0aSjfhqtaD83P30ge_1_U23Czg6rxuLWtO3DNlXfhcNZKdnUUn26vbi2P4sN4tmXBvroHryaIYvGgv3wZj8t6_n3ecD6FHqdhLW3MPValjWdVjRlLoXy3w_twNn13OjlJuscaEjMqaJ1YmzuleKac1kHPRHhDuaO6sIUTnHiaK0WN4dQE0OIyl2ZO-1R4ppkS1mj6AAZlVbp9iKk33ptUB9-SMSOcYMiyJ1yqkYxekwiGa23JRcvJIUMsg-qVf1VvBG9Qp5vGSKndFFSXX2U3Q6UgyirulTLMM6YDsPXKa8-dGdnCWhHBC7QIiRM_qN2o7v5CGDNSaMkxYi_BUhJ-d9BrGSas6Vev1S47h7GUW51H8GxTjV9iElzpqhW2wQQ4DIcieNia4EYkWgSsVYg0At4zzp7M_ZpyftHQiWPMTwTJH_17XI_hRhYAHmZOZOQABvXlyj0JgKzWT7tZ9wvBpD0p priority: 102 providerName: ProQuest – databaseName: Scholars Portal Open Access Journals dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELaqcuGCKM_QglIJlUtTHNub2JUK2lasKqSiPXSl3iI_6UqQLbupxP57ZpzsI6JwtR0_Zsb2N_H4MyHvWakpM7bImDE6E9rQzABuz5wSA1nk0urItn_1rbiciK83g5sdsiJU6AS4eNC1w_ekJvMfJ79_LT_DhD9DjxNc9o93t5u_vwsAOPhqCXjxj5jgAo3-qkP8cXHmaMQqnjUrfF-N8fZez79r6u1Ykdj_7-V7a__qx1ZubVajp-RJhzLTYWsWe2TH18_I0bhtd3mcXm9uXS2O06N0vCGwXj4nny4QgOIZfX2aDutm-nMa6ZqgxhFsg9FSU127dDxrMNgI0rcrfEEmoy_XF5dZ985CZgclbzLnCq-1ZNobAyqiKlguPTelK72SNPBCa26t5Bbwhmc-Z96EXAVhhFbOGv6S7Naz2r8mKQ82BJsbWBaYsMorgQR5yucGeeQNTcjJSpbVXUunUYEbgsKvHhR-Qs5R4uvCyIYdE2bz71U3uSpFtdMyaG1FEMIAJg06mCC9HbjSOZWQD6ivCq0IlGJ1d_UA-ozsV9UQYZMSOYXmDnolYa7ZfvZK49XKVCs8ihRIz8kTcrjOxi8xfq32s3ssg7Fr6Mkk5FVrIOsh8RJgUqnyhMie6fTG3M-pp7eRCRzddapo8eb_3d4njxlgMwx6YPSA7Dbze_8WsFRj3sXZ8Qc51iDc priority: 102 providerName: Scholars Portal |
| Title | Catestatin: Antimicrobial Functions and Potential Therapeutics |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/37242791 https://www.proquest.com/docview/2819480803 https://www.proquest.com/docview/2820017729/abstract/ https://pubmed.ncbi.nlm.nih.gov/PMC10220906 https://doaj.org/article/90ada8faac4f44b193fafbf8ec5d7dd9 |
| Volume | 15 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Nb5swFLfa7rLLtO6TrYuYNHWXkgB2AO8wKc0adZPSoamdekP-bCMtJGroof993zOQgLbTLiBhG4zfe7zfM88_E_IpTkUYS5UEsZQiYEKGgQTcHmjOxlkSZUo4tv35RXJ-xX5cj6_3SNKuhXFJ-0ouhuWf5bBc3LrcyvVSjdo8sVE-n2KUEvIwGe2T_ZTSTozuvr8U9ZTXy3UoxPSj9e1uengDCAi3NcEt4GgKDsrRc3Z8kqPu__sD3fFQ_ezJjjuaPSfPGhzpT-r-HpI9U74gx3ndhYcT_3K3rmpz4h_7-Y6i-uEl-TpFiIl_4csv_qSsFsuFI2SCO87A0Tld9EWp_XxVYToRXO_e8BW5mp1dTs-DZieFQI1TWgVaJ0aILBZGShBCyK2imaEy1anhWWhpIgRVKqMKEIWJTRQbaSNumWSCayXpa3JQrkrzlvjUKmtVJMHwY6a44Qwp8LiJJDLFy9Ajw3Ysi3VNmFFAoIFyKP4pB4-c4ohvKyPftbuwurspGqkXPBRaZFYIxSxjElCnFVbazKixTrXmHvmM8irQKkEoSjSLC6DPyG9VTBAYcRaF8LijXk2wJtUvbiVeNNa8KfBnI0MCTuqRj9tibIkZaqVZ3WMdzE7DWMUjb2oF2b5Sq2ceyXqq03vnfgmovuP6blX93f83fU-exoDMMOUhDo_IQXV3bz4AkqrkgDw5PbvIf8F5-vP3928DNyMBxznLBs6oHgEGCScY |
| link.rule.ids | 230,315,733,786,790,870,891,2115,2236,21416,24346,27955,27956,33777,33778,38549,43838,43928,53825,53827,74657,74767 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lc9MwEN6B9AAX3g9DATPDlEudypZiWxxgQiCTQltySDu9afSkGQYnNM6h_Hq0tvMwMBy4SrKsnV3tfpJWnwBeJZkkidJplCglIyYViZTH7ZHhrJenca5lxbZ_fJKOTtmn8955s-G2aNIqVz6xctRmpnGP_AAPfBiSINJ38x8RvhqFp6vNExrXYccH1iTvwM7gy9nhh_UuC6Fos7y-ukP9-v5gfrHZKl54NIRPnJBWUKq4-__00Fshqp0-uRWPhrdBrCSp01C-dZel6uqfv5E8_r-od-BWA1XDfm1bd-GaLe7B3riW7Go_nGyubi32w71wvGHBvroPbweIYvGgv3gT9oty-n1acT75Hoc-llbmHsrChONZiRlLvny7wwdwOvw4GYyi5rGGSPcyWkbGpFbKPJFWKa9nwp2muaUqM5nlOXE0lZJqnVPtQYtNbJxY5WLumGKSG63oQ-gUs8I-hpA67ZyOlfctCdPccoYse9zGCsnoFQmgu9KWmNecHMKvZVC94q_qDeA96nTdGCm1q4LZ5VfRzFDBiTQyd1Jq5hhTHtg66ZTLre6ZzBgewGu0CIET36tdy-b-gh8zUmiJPmIvzmLif7fbauknrG5Xr9QuGoexEBudB_ByXY1fYhJcYWdLbIMJcLgcCuBRbYJrkWjmsVbG4wDylnG2ZG7XFNOLik4c1_yEk_TJv8f1Am6MJsdH4ujw5PNTuJl4sIdZFAnZhU55ubTPPDgr1fNmBv4CtJFAEA |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELaglRAX3o9AgSChcml2ndibxBxAy5ZVy6Psoa16i_ykq4pk6WYP5dczk3gfAcSJq-0kHs14_Nn5_JmQV0kmaaJ0GiVKyYhLRSMFuD0ygg_yNM61bNT2vxylByf849ngzPOf5p5WucyJTaI2lcY98j7-8OEogsj6ztMiJvvjd7MfEd4ghX9a_XUa18k2QOQUFmLbo6-nh_urHRfKMH5Fe4yHwVq_PztfbxvPARnhdSe0M0E1Ov5_ZuuN6apLpdyYm8a3ycXSqpaSctFb1Kqnf_4m-Ph_zL5DbnkIGw7bmLtLrtnyHtmdtFZe7YXH6yNd871wN5ys1bGv7pO3I0S3SAAo34TDsp5-nzZaUPDGMcyxzTAIZWnCSVUjkwnKN1_4gJyMPxyPDiJ_iUOkBxmrI2NSK2WeSKsU-J8Kp1lumcpMZkVOHUulZFrnTAOYsYmNE6tcLBxXXAqjFXtItsqqtI9JyJx2TscKck7CtbCCo_qesLFCkXpFA9Jbeq6YtVodBaxx0NXFX10dkPfo31VjlNpuCqrLb4UfuYWg0sjcSam541wB4HXSKZdbPTCZMSIgrzE6CkwIEAJa-nMN0GeU1iqGiMkEjyl8bqfTEgay7lYvQ6DwiWRerP0fkJeranwSyXGlrRbYBolxuEwKyKM2HFcmsQwwWCbigOSdQO3Y3K0pp-eNzDjuBVBB0yf_7tcLcgMisvh8ePTpKbmZAAZEckVCd8hWfbmwzwCz1eq5H4y_ALjmSNM |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Catestatin%3A+Antimicrobial+Functions+and+Potential+Therapeutics&rft.jtitle=Pharmaceutics&rft.au=Jati%2C+Suborno&rft.au=Mahata%2C+Sumana&rft.au=Das%2C+Soumita&rft.au=Chatterjee%2C+Saurabh&rft.date=2023-05-20&rft.pub=MDPI+AG&rft.issn=1999-4923&rft.eissn=1999-4923&rft.volume=15&rft.issue=5&rft_id=info:doi/10.3390%2Fpharmaceutics15051550&rft.externalDocID=A750994100 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1999-4923&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1999-4923&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1999-4923&client=summon |