Renal Involvement in COVID-19: A Review of the Literature
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting...
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Published in | Infection and drug resistance Vol. 14; pp. 895 - 903 |
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Format | Journal Article |
Language | English |
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01.01.2021
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Abstract | Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management. |
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AbstractList | Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management. Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management. Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2 Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1 Nicola Coppola2 On behalf of the Vanvitelli COVID-19 Group1Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; 2Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania "Luigi Vanvitelli", Naples, Italy*These authors contributed equally to this workCorrespondence: Nicola CoppolaDepartment of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania "Luigi Vanvitelli", Via: L. Armanni 5, Naples, 80131, ItalyTel +39 081 5666719Fax +39 081 5666013Email nicola.coppola@unicampania.itAbstract: Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2 |
Audience | Academic |
Author | Migliaccio, Marco Giuseppe Ricciolino, Riccardo Di Mauro, Marco Verde, Nicoletta Coppola, Nicola Spiniello, Giorgio Mottola, Filiberto Fausto Carfora, Vincenzo |
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Copyright | 2021 Migliaccio et al. COPYRIGHT 2021 Dove Medical Press Limited 2021. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2021 Migliaccio et al. 2021 Migliaccio et al. |
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Keywords | COVID-19 SARS-CoV-2 acute kidney injury kidney injury |
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Snippet | Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various... Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1... |
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SubjectTerms | acute kidney injury Apoptosis Coronaviruses COVID-19 Creatinine Cytokines Health aspects Hypotension Infections Kidney diseases kidney injury Kidneys Literature reviews Lungs Medical prognosis Mortality Multiple organ dysfunction syndrome Pathogenesis Pneumonia Renal function Review sars-cov-2 Severe acute respiratory syndrome coronavirus 2 Virus diseases Viruses |
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Title | Renal Involvement in COVID-19: A Review of the Literature |
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