Renal Involvement in COVID-19: A Review of the Literature

Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting...

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Published inInfection and drug resistance Vol. 14; pp. 895 - 903
Main Authors Migliaccio, Marco Giuseppe, Di Mauro, Marco, Ricciolino, Riccardo, Spiniello, Giorgio, Carfora, Vincenzo, Verde, Nicoletta, Mottola, Filiberto Fausto, Coppola, Nicola
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Abstract Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
AbstractList Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management. Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2
Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1 Nicola Coppola2 On behalf of the Vanvitelli COVID-19 Group1Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; 2Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania "Luigi Vanvitelli", Naples, Italy*These authors contributed equally to this workCorrespondence: Nicola CoppolaDepartment of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania "Luigi Vanvitelli", Via: L. Armanni 5, Naples, 80131, ItalyTel +39 081 5666719Fax +39 081 5666013Email nicola.coppola@unicampania.itAbstract: Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2
Audience Academic
Author Migliaccio, Marco Giuseppe
Ricciolino, Riccardo
Di Mauro, Marco
Verde, Nicoletta
Coppola, Nicola
Spiniello, Giorgio
Mottola, Filiberto Fausto
Carfora, Vincenzo
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Keywords COVID-19
SARS-CoV-2
acute kidney injury
kidney injury
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Snippet Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various...
Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1...
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SubjectTerms acute kidney injury
Apoptosis
Coronaviruses
COVID-19
Creatinine
Cytokines
Health aspects
Hypotension
Infections
Kidney diseases
kidney injury
Kidneys
Literature reviews
Lungs
Medical prognosis
Mortality
Multiple organ dysfunction syndrome
Pathogenesis
Pneumonia
Renal function
Review
sars-cov-2
Severe acute respiratory syndrome coronavirus 2
Virus diseases
Viruses
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Title Renal Involvement in COVID-19: A Review of the Literature
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