Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules - Usanov, Dmitry L.; Chan, Alix I.; Maianti, Juan Pablo; Liu, David R. (Nature chemistry, 2018)
Keywords: 631/92/2132/605; 639/638/309/507; 639/638/92/2132; Analytical Chemistry; Biochemistry; Biological activity; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Coding; Codon; Codons; Computation; Computer applications; Deoxyribonucleic acid; DNA; DNA - chemistry; DNA biosynthesis; Enzyme inhibitors; Enzymes; Inorganic Chemistry; Insulin; Insulysin; Macrocyclic Compounds - chemistry; Molecular chains; Organic Chemistry; Physical Chemistry; Physical properties; Production methods; Purification; Small Molecule Libraries - chemistry; Software; Stereochemistry; Stereoisomerism; Templates, Genetic