Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes

• Published in: Nature communications Vol. 9; no. 1; pp. 611 - 10
• Main Authors: Zhao, Changgui, Guo, Donghui, Munkerup, Kristin, Huang, Kuo-Wei, Li, Fangyi, Wang, Jian
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.02.2018; Nature Publishing Group; Nature Portfolio
• Subjects: 639/638/403/933; 639/638/77/883; 639/638/77/889; Active control; Carbenes; Catalysis; Catalysts; Chemical bonds; Chemical reactions; Chemical synthesis; Diketones; Enantiomers; Humanities and Social Sciences; Intermediates; Lewis acid; multidisciplinary; Organic chemistry; Oxidizing agents; Science; Science (multidisciplinary); Substrates; Transformations

Axially chiral molecules are among the most valuable substrates in organic synthesis. They are typically used as chiral ligands or catalysts in asymmetric reactions. Recent progress for the construction of these chiral molecules is mainly focused on the transition-metal-catalyzed transformations. He...