Effect of a Multispecies Synbiotic Supplementation on Body Composition, Antioxidant Status, and Gut Microbiomes in Overweight and Obese Subjects: A Randomized, Double-Blind, Placebo-Controlled Study

• Published in: Nutrients Vol. 15; no. 8; p. 1863
• Main Authors: Oraphruek, Piyarat, Chusak, Charoonsri, Ngamukote, Sathaporn, Sawaswong, Vorthon, Chanchaem, Prangwalai, Payungporn, Sunchai, Suantawee, Tanyawan, Adisakwattana, Sirichai
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 13.04.2023; MDPI
• Subjects: antioxidant activity; Antioxidants; Antioxidants - pharmacology; Bacteroidetes; blood; Body Composition; Body fat; Body mass index; Cytokines; Diet therapy; Dietary supplements; digestive system; Double-Blind Method; Double-blind studies; Firmicutes; fructooligosaccharides; Gastrointestinal Microbiome; Gastrointestinal system; Health aspects; Humans; Inflammation; intestinal microorganisms; malondialdehyde; maltodextrins; Metabolism; microbiome; Microbiota; Microbiota (Symbiotic organisms); Obesity; Obesity - therapy; Overweight; Overweight - therapy; Oxidative stress; Physiological aspects; placebos; Plasma; Prebiotics; Probiotics; Synbiotics; Tumor necrosis factor-TNF; waist circumference; Weight control; Thailand; St Louis Missouri; United States > US; Germany; Bangkok Thailand; probiotic; prebiotic; gut microbiota; synbiotic; overweight and obesity

Studies investigating the effect of multispecies synbiotic supplementation in obesity management are limited. The current study was performed to evaluate the effects of multispecies probiotics mixed with fructooligosaccharides on body composition, antioxidant status, and gut microbiome composition i...