Research Progress of Aluminum Phosphate Adjuvants and Their Action Mechanisms

• Published in: Pharmaceutics Vol. 15; no. 6; p. 1756
• Main Authors: Zhang, Ting, He, Peng, Guo, Dejia, Chen, Kaixi, Hu, Zhongyu, Zou, Yening
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.06.2023; MDPI
• Subjects: Adsorption; Aluminum; Aluminum hydroxide; aluminum phosphate adjuvants; aluminum phosphate improvement; Antigens; Immune response; immune stimulation mechanism; Immunotherapy; Medical research; Phosphates; preclinical and clinical; Review; Vaccines; preclinical and clinical; immune stimulation mechanism; aluminum phosphate improvement; aluminum phosphate adjuvants

Although hundreds of different adjuvants have been tried, aluminum-containing adjuvants are by far the most widely used currently. It is worth mentioning that although aluminum-containing adjuvants have been commonly applied in vaccine production, their acting mechanism remains not completely clear....