Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9 - Byambaa, Suvd; Uosaki, Hideki; Hara, Hiromasa; Nagao, Yasumitsu; Abe, Tomoyuki; Shibata, Hiroaki; Nureki, Osamu; Ohmori, Tsukasa; Hanazono, Yutaka (Experimental Animals, 2020)
Keywords: animal model; clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9; CRISPR; Exons; Gene deletion; Genetic disorders; genome-editing; II2rg; Insertion; Interleukin 2; Interleukins; Lymphocytes; Lymphocytes B; Lymphocytes T; mRNA; Mutants; Mutation; Nucleotides; Original; Peripheral blood; Phenotypes; Proteins; Rodents; Severe combined immunodeficiency; X-linked severe combined immunodeficiency (X-SCID); Zygotes; X-linked severe combined immunodeficiency (X-SCID); clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9; II2rg; animal model; genome-editing