MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

• Published in: Analyst Vol. 142; no. 3; pp. 442 - 448
• Main Authors: Burnum-Johnson, Kristin E, Kyle, Jennifer E, Eisfeld, Amie J, Casey, Cameron P, Stratton, Kelly G, Gonzalez, Juan F, Habyarimana, Fabien, Negretti, Nicholas M, Sims, Amy C, Chauhan, Sadhana, Thackray, Larissa B, Halfmann, Peter J, Walters, Kevin B, Kim, Young-Mo, Zink, Erika M, Nicora, Carrie D, Weitz, Karl K, Webb-Robertson, Bobbie-Jo M, Nakayasu, Ernesto S, Ahmer, Brian, Konkel, Michael E, Motin, Vladimir, Baric, Ralph S, Diamond, Michael S, Kawaoka, Yoshihiro, Waters, Katrina M, Smith, Richard D, Metz, Thomas O
• Format: Journal Article Web Resource
• Language: English
• Published: England Royal Society of Chemistry 26.01.2017
• Subjects: Bacteria; Bacteria - isolation & purification; BASIC BIOLOGICAL SCIENCES; Cell Line; Environmental Molecular Sciences Laboratory; Epithelial Cells; Exposure; Extraction; Humans; Inactivation; Lipids; Lipids - analysis; Mass Spectrometry; Membranes; Metabolomics; Pathogens; Proteins; Proteomics; Virus Inactivation; Viruses; Viruses - isolation & purification

The continued emergence and spread of infectious agents is of great concern, and systems biology approaches to infectious disease research can advance our understanding of host-pathogen relationships and facilitate the development of new therapies and vaccines. Molecular characterization of infectio...