Acute effects of vasoactive drug treatment on brachial artery reactivity

• Published in: Journal of the American College of Cardiology Vol. 40; no. 4; pp. 761 - 765
• Main Authors: Gokce, Noyan, Holbrook, Monika, Hunter, Liza M, Palmisano, Joseph, Vigalok, Elena, Keaney, John F, Vita, Joseph A
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 21.08.2002; Elsevier Science; Elsevier Limited
• Subjects: Adult; Analysis of Variance; Biological and medical sciences; Blood pressure; Brachial Artery - drug effects; Brachial Artery - physiology; Cardiology; Cardiovascular Agents - pharmacology; Cardiovascular disease; Cardiovascular system; Coronary Disease - physiopathology; Coronary vessels; Double-Blind Method; Enalapril - pharmacology; Endothelium; Endothelium, Vascular - drug effects; Endothelium, Vascular - physiology; Enzymes; Felodipine - pharmacology; Female; Flow velocity; Heart; Heart rate; Humans; Hypertension; Investigative techniques of hemodynamics; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Metoprolol - pharmacology; Models, Cardiovascular; Reference Values; Reproducibility of Results; Risk assessment; Software; Studies; Ultrasonic imaging; Variance analysis; Vasodilation - drug effects; ACE; NMD; FMD; ANOVA; CAD; BMI; Human; Regional blood flow; Pharmacologic test; Vasodilator agent; Acute; Brachial artery; Exploration; Endothelium; Non invasive method; Vasoconstrictor agent; Hemodynamics; Technique; Vascular wall

The goal of this study was to investigate whether concomitant therapy with vasoactive medications alters the results of noninvasive assessment of endothelial function. Ultrasound assessment of brachial artery flow-mediated dilation is emerging as a useful clinical tool. The current practice of withh...