Non-targeted metabolomic study in plasma in rats with post-traumatic osteoarthritis model - Han, Peng-fei; Li, Xi-yong; Zhang, Chang-peng; Liao, Chang-sheng; Wang, Wei-wei; Li, Yuan (PloS one, 2025)
Keywords: Adenosine; Adenosine triphosphate; Age; Amino acids; AMP; Analysis; Animal models; Animals; Bioinformatics; Biology and Life Sciences; Biomarkers; Biomarkers - blood; Care and treatment; Cartilage; Chromatography; Composition; Computational biology; Computer and Information Sciences; Correlation analysis; Data analysis; Diagnosis; Dichloroacetic acid; Disease Models, Animal; Experiments; Female; Human tissues; Isocitric acid; Ketoglutaric acid; Knee; Lactose; Linolenic acid; Linolenic acids; Mass spectrometry; Medicine and Health Sciences; Menadione; Metabolism; Metabolites; Metabolome; Metabolomics; Metabolomics - methods; Osteoarthritis; Osteoarthritis - blood; Osteoarthritis - etiology; Osteoarthritis - metabolism; Phenanthridine; Proteomics; Rats; Rats, Sprague-Dawley; Reproducibility; Research and Analysis Methods; Research methodology; Risk factors; Scientific imaging; Software; Systems stability; Temperature; Trauma; China