A review on recent advances on nobiletin in central and peripheral nervous system diseases

• Published in: European journal of medical research Vol. 28; no. 1; pp. 1 - 12
• Main Authors: Pang, Yueshan, Xiong, Juan, Wu, You, Ding, Weijun
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 06.11.2023; BioMed Central; BMC
• Subjects: Apoptosis; Bioavailability; Boolean; Brain research; Central nervous system (CNS); Citrus; Citrus fruits; Disease; Enteric nervous system (ENS); Enzymes; Flavonoids; Hypoxia; Inflammation; Keywords; Kinases; Memory; Microbiota; Nervous system; Nervous system diseases; Neurological disorders; Neurons; Neuroprotection; Nobiletin; Oral administration; Permeability; Phosphorylation; Polymethoxyflavones; Protein binding; Proteins; R&D; Research & development; Subject heading schemes
• ISSN: 2047-783X; 0949-2321; 2047-783X
• DOI: 10.1186/s40001-023-01450-7

In recent years, the role of nobiletin in neuronal disorders has received extensive attention. However, the study of nobiletin in the peripheral nervous system is limited. Nobiletin, as a compound with high fat solubility, high bioavailability and low toxicity, has been extensively studied. Accumula...