Artemether-lumefantrine treatment failure of uncomplicated Plasmodium falciparum malaria in travellers coming from Angola and Mozambique

• Published in: International journal of infectious diseases Vol. 110; pp. 151 - 154
• Main Authors: Silva-Pinto, André, Domingos, João, Cardoso, Margarida, Reis, Ana, Benavente, Ernest Diez, Caldas, João Paulo, Conceição, Cláudia, Toscano, Cristina, Baptista-Fernandes, Teresa, Clark, Taane G., Mansinho, Kamal, Campino, Susana, Nogueira, Fatima
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.09.2021; Elsevier
• Subjects: Angola - epidemiology; Antimalarials - therapeutic use; Artemether - therapeutic use; Artemether, Lumefantrine Drug Combination - therapeutic use; Artemether-Lumefantrine; Case Report; Humans; Malaria, Falciparum - drug therapy; Malaria, Falciparum - epidemiology; Male; Middle Aged; Mozambique - epidemiology; Plasmodium falciparum; Plasmodium falciparum - genetics; Therapeutic failure; Treatment Failure; Angola; Mozambique; Therapeutic failure; Plasmodium falciparum; Artemether-Lumefantrine

•Artemether-lumefantrine (AL) treatment failure of imported malaria in Portugal•AL treatment failure in the presence of wild-type pfk13 and pfmdr1•Is the standard 3-day course of AL sufficient to ensure parasite clearance?•AL increasing treatment failures urges closer immediate follow up of malaria...