Systemic immune-inflammation index is associated with clinical outcome of acute ischemic stroke patients after intravenous thrombolysis treatment

• Published in: PloS one Vol. 20; no. 3; p. e0319920
• Main Authors: Zhou, Yuanfeng, Yang, Qian, Zhou, Zhangming, Yang, Xin, Zheng, Danni, He, Zhongchun, Liu, Yizhou, Xu, Tianzhu, Yin, Ying, Wei, Wenhui, Si, Chunli, Zhang, Bozhi, Yu, Jianping
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 27.03.2025; Public Library of Science (PLoS)
• Subjects: Administration, Intravenous; Aged; Aged, 80 and over; Biology and Life Sciences; Blood; Blood Platelets; Brain; Brain Edema; Brain Ischemia - drug therapy; Brain Ischemia - immunology; Brain research; Care and treatment; Clinical outcomes; Edema; Female; Hemorrhage; Humans; Inflammation; Inflammation - immunology; Intravenous administration; Intravenous therapy; Ischemia; Ischemic Stroke - drug therapy; Ischemic Stroke - immunology; Laboratories; Leukocytes (neutrophilic); Lymphocytes; Magnetic resonance imaging; Male; Medical examination; Medical prognosis; Medicine and Health Sciences; Middle Aged; Neutrophils; Normal distribution; Patient outcomes; Patients; Prognosis; Regression analysis; Retrospective Studies; ROC Curve; Sensitivity; Statistical analysis; Stroke; Stroke patients; Thrombolysis; Thrombolytic Therapy; Treatment Outcome; Tumors; China

The systemic immune-inflammation index (SII) has been proven to predict the outcome in cancerous and non-cancerous diseases. We aimed to investigate the relationship between SII and other inflammatory markers and the prognosis in patients receiving intravenous thrombolysis (IVT). Acute ischemic stro...