Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans

• Vydáno v: International Journal of Obesity Ročník 35; číslo 1; s. 99 - 108
• Hlavní autoři: Ara, I, Larsen, S, Stallknecht, B, Guerra, B, Morales-Alamo, D, Andersen, J.L, Ponce-González, J.G, Guadalupe-Grau, A, Galbo, H, Calbet, J.A.L, Helge, J.W
• Typ dokumentu: Článek v odborném časopise
• Jazyk: angličtina
• Vydáno: London Nature Publishing Group UK 01.01.2011; Nature Publishing Group
• Témata: 631/443/319/2723; 631/443/319/333; 692/699/2743/393; adiponectin; Adiponectin - blood; Adult; Age Distribution; Arm; Biological and medical sciences; biopsy; blood; Blotting, Western; Body Mass Index; Calorimetry; Calorimetry, Indirect; Care and treatment; Dehydrogenases; Diseases; Energy Metabolism; Enzymatic activity; enzyme activity; Enzymes; Epidemiology; exercise; Exercise intensity; Exercise Test; Fatty acids; Fatty Acids, Nonesterified; Fatty Acids, Nonesterified - blood; free fatty acids; Health Promotion and Disease Prevention; Humans; Hypotheses; Insulin resistance; Internal Medicine; Kinases; Leg; leptin; Lipid Metabolism; Male; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; metabolism; Mitochondria; Mitochondria - metabolism; Mitochondrial diseases; muscle fibers; Muscle, Skeletal; Muscle, Skeletal - metabolism; Muscle, Skeletal - physiopathology; Muscles; Musculus; Nutrition research; Obesity; Obesity - blood; Obesity - metabolism; Obesity - physiopathology; original-article; Overweight persons; Oxidation; Oxidation-Reduction; Oxidation-reduction reaction; oxygen; Phosphorylation; Physical fitness; Physiological aspects; physiopathology; Prevalence studies (Epidemiology); Prognosis; Prospective Studies; Public Health; Risk factors; Surveys and Questionnaires; triacylglycerols; Triglycerides; Triglycerides - blood; Weight control; weight loss; Denmark; Spain; weight loss; adiponectin; lipid oxidation; physical activity; Physical exercise; Human; Obesity; Nutrition; Nutrition disorder; Weight loss; Lipids; Metabolic diseases; Normal; Adiponectin; Leg; Mitochondria; Fat; Muscle; Oxidation; Arm; Nutritional status
• On-line přístup: Získat plný text
• ISSN: 0307-0565; 1476-5497; 1476-5497
• DOI: 10.1038/ijo.2010.123

Aim/hypothesis: The aim of this study was to investigate mitochondrial function, fibre-type distribution and substrate oxidation during exercise in arm and leg muscles in male postobese (PO), obese (O) and age- and body mass index (BMI)-matched control (C) subjects. The hypothesis of the study was t...