Microarray Analysis of Differentially Expressed Fetal Genes in Placental Tissue Derived from Early and Late Onset Severe Pre-eclampsia

• Published in: Placenta (Eastbourne) Vol. 28; no. 5; pp. 487 - 497
• Main Authors: Nishizawa, H., Pryor-Koishi, K., Kato, T., Kowa, H., Kurahashi, H., Udagawa, Y.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.05.2007; Elsevier
• Subjects: Adult; Biological and medical sciences; Blood Pressure; Body Weight; Chorionic Villi - physiology; Embryology: invertebrates and vertebrates. Teratology; Female; Fetus - physiology; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation; Gene ontology; Genetic Predisposition to Disease; Gestational Age; Humans; Internal Medicine; Microarray analysis; Obstetrics and Gynecology; Oligonucleotide Array Sequence Analysis; Placenta - anatomy & histology; Placenta - pathology; Placenta - physiology; Pre-eclampsia; Pre-Eclampsia - genetics; Pregnancy; RNA - genetics; RNA - isolation & purification; Gene ontology; Pre-eclampsia; Microarray analysis; Late; Pregnancy disorders; Fetal membrane; Gene expression; Pregnancy toxemia; Tissue; Vertebrata; Mammalia; Placenta; Preeclampsia; Fetus; Early; Severe

Although it has been well documented that pre-eclampsia is caused by a combination of maternal and fetal susceptibility genes, little is known about the precise etiology of this complicated disorder. To investigate how the expression of fetal genes contributes to the mechanisms underlying the progre...