Clinical and Laboratory Characteristics That Differentiate Hereditary Angioedema in 72 Patients with Angioedema

• Published in: Allergology international Vol. 63; no. 4; pp. 595 - 602
• Main Authors: Ohsawa, Isao, Honda, Daisuke, Nagamachi, Seiji, Hisada, Atsuko, Shimamoto, Mamiko, Inoshita, Hiroyuki, Mano, Satoshi, Tomino, Yasuhiko
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 2014; Elsevier
• Subjects: Adolescent; Adult; Age of Onset; Aged; Algorithms; Angioedema - blood; Angioedema - diagnosis; Angioedemas, Hereditary - blood; Angioedemas, Hereditary - diagnosis; Biomarkers - blood; Biomarkers - metabolism; C1-inhibitor; Child; Complement C1 Inhibitor Protein; Complement C4; d-dimer; Diagnosis, Differential; Female; Fibrin Fibrinogen Degradation Products; hereditary angioedema (HAE); Humans; Male; Middle Aged; Mucous Membrane - immunology; Mucous Membrane - pathology; Subcutaneous Tissue - immunology; Subcutaneous Tissue - pathology; suffocation; Young Adult; C1-inhibitor; C4; hereditary angioedema (HAE); suffocation; d-dimer

Hereditary angioedema (HAE) is a rare but life-threatening condition that results from mutations in C1-inhibitor (C1-INH). Since distinguishing HAE from other causes of angioedema (AE) is a critical problem in emergencies, the objective of the present study was to clarify the differences between HAE...