High circulating CD39+ regulatory T cells predict poor survival for sepsis patients

• Published in: International journal of infectious diseases Vol. 30; no. C; pp. 57 - 63
• Main Authors: Huang, Huihuang, Xu, Ruonan, Lin, Fang, Bao, Chunmei, Wang, Siyu, Ji, Chengcheng, Li, Ke, Jin, Lei, Mu, Jingsong, Wang, Yonggang, Li, Lei, Sun, Lijian, Xu, Biao, Zhang, Zheng, Wang, Fu-Sheng
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.01.2015; Elsevier
• Subjects: Adult; Aged; Antigens, CD - analysis; Apyrase - analysis; CD39; Female; Humans; Infectious Disease; Male; Middle Aged; Prognosis; Pulmonary/Respiratory; Regulatory T cell; Sepsis; Sepsis - immunology; Sepsis - mortality; Survival Analysis; Systemic Inflammatory Response Syndrome - immunology; Systemic Inflammatory Response Syndrome - mortality; T-Lymphocytes, Regulatory - immunology; CD39; Sepsis; Prognosis; Regulatory T cell

•Regulatory T cells (Tregs) have been implicated in the pathogenesis of sepsis by regulating the immune response.•CD39+ Tregs have been reported to be a more powerful subset of Tregs in suppressing the immune response and play a key role in the pathogenesis of some inflammatory diseases.•The role of...