Beneficial effects of cerebellar tDCS on motor learning are associated with altered putamen-cerebellar connectivity: A simultaneous tDCS-fMRI study

• Published in: NeuroImage (Orlando, Fla.) Vol. 223; p. 117363
• Main Authors: Liebrand, Matthias, Karabanov, Anke, Antonenko, Daria, Flöel, Agnes, Siebner, Hartwig R., Classen, Joseph, Krämer, Ulrike M., Tzvi, Elinor
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2020; Elsevier Limited; Elsevier
• Subjects: Adult; Brain Mapping; Cerebellum; Cerebellum - physiology; Cortex (frontal); Cortex (motor); Electrical stimulation of the brain; ESB; Explicit knowledge; Female; fMRI; Frontal gyrus; Functional magnetic resonance imaging; Humans; Learning - physiology; Magnetic Resonance Imaging; Male; Middle Aged; Motor Cortex - physiology; Motor sequence learning; Motor skill learning; Neural Pathways - physiology; Neuroimaging; Psychomotor Performance - physiology; Putamen; Putamen - physiology; Reaction Time; Reaction time task; Rehabilitation; Supplementary motor area; tDCS; Transcranial Direct Current Stimulation; Young Adult; Cerebellum; RT; M1; IPL; RmANOVA; RND; MNI; GLM; IFG; BMA; BOLD; CB; STIM; Pu; SMA; PMC; DCN; DCM; fMRI; tDCS; Motor sequence learning; SMP; SRTT; COND; SEQ

Non-invasive transcranial stimulation of cerebellum and primary motor cortex (M1) has been shown to enhance motor learning. However, the mechanisms by which stimulation improves learning remain largely unknown. Here, we sought to shed light on the neural correlates of transcranial direct current sti...