LDL cholesterol as a novel risk factor for contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention

• Published in: Atherosclerosis Vol. 237; no. 2; pp. 453 - 459
• Main Authors: Liu, Yuan-hui, Liu, Yong, Chen, Ji-yan, Zhou, Ying-ling, Chen, Zhu-jun, Yu, Dan-qing, Luo, Jian-fang, Li, Hua-long, He, Yi-ting, Ye, Piao, Ran, Peng, Guo, Wei, Tan, Ning
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.12.2014
• Subjects: Acute Kidney Injury - pathology; Aged; Cardiovascular; Cholesterol, LDL - blood; Contrast Media - adverse effects; Contrast Media - chemistry; Contrast-induced acute kidney injury; Creatinine - blood; Female; Hospitalization; Humans; Incidence; Low density lipoprotein cholesterol; Male; Middle Aged; Myocardial Infarction - blood; Odds Ratio; Percutaneous Coronary Intervention; Prospective Studies; Regression Analysis; Risk Factors; Treatment Outcome; Contrast-induced acute kidney injury; Low density lipoprotein cholesterol; Percutaneous coronary intervention

Background: Low density lipoprotein cholesterol (LDL-C) is associated with endothelial dysfunction, inflammation and increased vasoconstriction, which are involved in the development of contrast-induced acute kidney injury (CI-AKI). However, whether LDL-C is an independent risk factor of CI-AKI in p...