Insight into 2019 novel coronavirus — An updated interim review and lessons from SARS-CoV and MERS-CoV

• Published in: International journal of infectious diseases Vol. 94; pp. 119 - 124
• Main Authors: Xie, Mingxuan, Chen, Qiong
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.05.2020; The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases; Elsevier
• Subjects: 2019- nCoV; Animals; Betacoronavirus; Coronavirus Infections - therapy; COVID-19; Humans; MERS- CoV; Middle East Respiratory Syndrome Coronavirus; Pandemics; Pneumonia, Viral - therapy; SARS-CoV; SARS-CoV- 2; Severe acute respiratory syndrome-related coronavirus; COVID-19; SARS-CoV- 2; 2019- nCoV; SARS-CoV; MERS- CoV

•The COVID-19 has a high R0, a long incubation period, and a short serial interval.•The COVID-19 has a general low CFR, but much higher in patients with comorbidities.•The spike protein binding to ACE2 may explain the high R0 of COVID-19.•Autopsy showed more exudative lesions, and less fibrosis and...