The revised Cochrane risk of bias tool for randomized trials (RoB 2) showed low interrater reliability and challenges in its application

• Published in: Journal of clinical epidemiology Vol. 126; pp. 37 - 44
• Main Authors: Minozzi, Silvia, Cinquini, Michela, Gianola, Silvia, Gonzalez-Lorenzo, Marien, Banzi, Rita
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2020; Elsevier Limited
• Subjects: Agreements; Algorithms; Bias; Confidence intervals; Cross-Sectional Studies; Data Analysis; Data Collection - methods; Domains; Epidemiology; Humans; Internal Medicine; Interrater reliability; Intervention; Judgment - physiology; Knowledge; Outcome Assessment, Health Care; Randomization; Randomized controlled trials; Randomized Controlled Trials as Topic; Reliability analysis; Reproducibility of Results; Research Design; Research Personnel - statistics & numerical data; Research Personnel - trends; Risk; Risk of bias; RoB 2; Systematic reviews; Terminology; Systematic reviews; RoB 2; Interrater reliability; Risk of bias; Randomized controlled trials

The objective of the study is to assess the interrater reliability (IRR) and usability of the revised Cochrane risk of bias tool for randomized trials (RoB 2). This is a cross-sectional study. Four raters independently applied RoB 2 on the primary outcome of a random sample of individually randomize...