A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer’s disease

• Published in: Ultrasonography (Seoul, Korea) Vol. 40; no. 4; pp. 512 - 519
• Main Authors: Jeong, Hyeonseok, Im, Jooyeon Jamie, Park, Jong-Sik, Lee, Wonhye, Yoo, Seung-Schik, Song, In-Uk, Chung, Yong-An
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Society of Ultrasound in Medicine 01.10.2021; 대한초음파의학회
• Subjects: Acoustics; Alzheimer's disease; Bandwidths; Brain; cognitive function; Contrast agents; Dementia; low-intensity transcranial focused ultrasound; Magnetic resonance imaging; Medical imaging; Memory; Mental disorders; Neuropsychology; Original; Patients; regional cerebral metabolic rate of glucose; Tomography; Ultrasonic imaging; 방사선과학; United States > US; Low-intensity transcranial focused ultrasound; Regional cerebral metabolic rate of glucose; Alzheimer’s disease; Cognitive function

Purpose: Increasing attention has been paid to low-intensity transcranial focused ultrasound (tFUS) for its potential therapeutic effects in Alzheimer's disease (AD). While preclinical studies have shown promising therapeutic effects of low-intensity tFUS in AD models, its efficacy and safety r...