Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2

• Published in: International journal of infectious diseases Vol. 113; pp. S82 - S87
• Main Authors: Petrone, Linda, Petruccioli, Elisa, Vanini, Valentina, Cuzzi, Gilda, Gualano, Gina, Vittozzi, Pietro, Nicastri, Emanuele, Maffongelli, Gaetano, Grifoni, Alba, Sette, Alessandro, Ippolito, Giuseppe, Migliori, Giovanni Battista, Palmieri, Fabrizio, Goletti, Delia
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.12.2021; The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases; Elsevier
• Subjects: Antigens, Bacterial - immunology; Antigens, Viral - immunology; Co-infection; Coinfection; COVID-19; COVID-19 - immunology; Humans; IFN-gamma response; Interferon-gamma - immunology; M. tuberculosis; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tuberculosis; Tuberculosis - immunology; Whole blood assay; COVID-19; Tuberculosis; Co-infection; IFN-gamma response; M. tuberculosis; Whole blood assay

•TB and COVID-19 coinfection does not affect M. tuberculosis-specific response.•TB and COVID-19 coinfection limits the ability to in vitro respond to SARS-CoV-2.•Latent TB infection does not affect the ability to in vitro respond to SARS-CoV-2. The interaction of COVID-19 and tuberculosis (TB) are s...