Quantifying the confounding effect of pigmentation on measured skin tissue optical properties: a comparison of colorimetry with spatial frequency domain imaging

• Published in: Journal of biomedical optics Vol. 27; no. 3; p. 036002
• Main Authors: Phan, Thinh, Rowland, Rebecca, Ponticorvo, Adrien, Le, Binh Cong, Sharif, Seyed A, Kennedy, Gordon T, Wilson, Robert H, Durkin, Anthony J
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.03.2022; SPIE; S P I E - International Society for
• Subjects: Absorption; Colorimetry; Correlation coefficient; Correlation coefficients; Dermatology; Epidermis; Forearm; Free radicals (Chemistry); Frequency dependence; Frequency domain analysis; Gender; Hemoglobin; Humans; Imaging; Imaging techniques; Interaction models; Medical imaging; Melanin; Optical Imaging - methods; Optical properties; Parameters; Pigmentation; Skin; Skin - diagnostic imaging; Skin Pigmentation; Tristimulus colorimetry; Wavelengths; California; United States > US; spatial frequency domain imaging; scattering coefficient; multispectral imaging; absorption coefficient; pigmentation; melanin; skin; colorimeter; epidermis

Significance: Spatial frequency domain imaging (SFDI) is a wide-field diffuse optical imaging technique for separately quantifying tissue reduced scattering (μs  ′  ) and absorption (μa) coefficients at multiple wavelengths, providing wide potential utility for clinical applications such as burn wou...