Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice - Mayo, Leah M.; Asratian, Anna; Lindé, Johan; Holm, Lovisa; Nätt, Daniel; Augier, Gaëlle; Stensson, Niclas; Vecchiarelli, Haley A.; Balsevich, Georgia; Aukema, Robert J.; Ghafouri, Bijar; Spagnolo, Primavera A.; et al. (Molecular psychiatry, 2020)
Keywords: 631/208; 631/378; 64/110; 692/699/476; 82/58; Adolescent; Adult; Alleles; Amidohydrolases - antagonists & inhibitors; Amidohydrolases - genetics; Amidohydrolases - metabolism; Amygdala; Analysis; Anandamide; Animals; Arachidonic Acids - metabolism; Behavior; Behavioral health care; Behavioral Sciences; Biological Psychology; Endocannabinoids - metabolism; Enzymes; Evidence-based medicine; Extinction behavior; Extinction, Psychological - drug effects; Fatty acids; Fatty-acid amide hydrolase; Fear - drug effects; Fear conditioning; Female; Genotypes; Homozygotes; Humans; Hydrolase; Male; Medicine; Medicine & Public Health; Mental disorders; Mice; Neurosciences; Pharmacotherapy; Polyunsaturated Alkamides - metabolism; Post traumatic stress disorder; Prefrontal cortex; Protective Agents - metabolism; Psychiatry; Stress Disorders, Post-Traumatic - drug therapy; Stress Disorders, Post-Traumatic - genetics; Stress Disorders, Post-Traumatic - metabolism; Stress Disorders, Post-Traumatic - psychology; Young Adult