Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis - Middleton, Michael S.; Heba, Elhamy R.; Hooker, Catherine A.; Bashir, Mustafa R.; Fowler, Kathryn J.; Sandrasegaran, Kumar; Brunt, Elizabeth M.; Kleiner, David E.; Doo, Edward; Van Natta, Mark L.; Lavine, Joel E.; Neuschwander-Tetri, Brent A.; et al. (Gastroenterology (New York, N.Y. 1943), 2017)
Keywords: Adiposity; Adult; Area Under Curve; Biopsy; Chenodeoxycholic Acid - analogs & derivatives; Chenodeoxycholic Acid - therapeutic use; Direct Comparison; Female; FLINT; Gastroenterology and Hepatology; Humans; Liver - pathology; Magnetic Resonance Imaging - methods; Male; Middle Aged; NAFLD; Non-alcoholic Fatty Liver Disease - diagnostic imaging; Non-alcoholic Fatty Liver Disease - pathology; Non-Invasive; ROC Curve; Single-Blind Method; NAFLD; MRI; Direct Comparison; CI; ROC; AUROC; EOT; NASH; ROI; PDFF; RCC; FLINT; Non-Invasive; CRN; positive predictive value; NAS; magnetic resonance spectroscopy; Digital Imaging and Communications in Medicine; nonalcoholic steatohepatitis; clinical research network; NAFLD activity score; Hematoxylin and eosin; DCC; body mass index; H&E; proton density fat fraction; nonalcoholic fatty liver disease; time to echo; CAP; GRE; negative predictive value; standard deviation; gradient-recalled echo; magnetic resonance imaging; PPD; area under receiving operating curve; MRS; SD; Data Coordinating Committee; non-invasive; NPV; Farnesoid X Receptor Ligand Obeticholic Acid in NASH Treatment Trial; DICOM; receiver operating characteristic; BMI; direct comparison; end of treatment; TE; repeat time; Radiology Coordinating Center; region of interest; confidence interval; TR