Insula functional connectivity in schizophrenia

• Published in: Schizophrenia research Vol. 220; pp. 69 - 77
• Main Authors: Sheffield, Julia M., Rogers, Baxter P., Blackford, Jennifer Urbano, Heckers, Stephan, Woodward, Neil D.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2020
• Subjects: Cognition; Insula; Negative symptoms; Positive symptoms; Psychiatric/Mental Health; Resting-state functional connectivity; Schizophrenia; Schizophrenia; Insula; Resting-state functional connectivity; Negative symptoms; Cognition; Positive symptoms

The insula is structurally abnormal in schizophrenia, demonstrating reductions in volume, cortical thickness, and altered gyrification during prodromal, early and chronic stages of the illness. Despite compelling structural alterations, less is known about its functional connectivity, limited by stu...