Investigation of the evolution of radiation-induced lung damage using serial CT imaging and pulmonary function tests

• Published in: Radiotherapy and oncology Vol. 148; pp. 89 - 96
• Main Authors: Veiga, Catarina, Chandy, Edward, Jacob, Joseph, Yip, Natalie, Szmul, Adam, Landau, David, McClelland, Jamie R.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.07.2020; Elsevier Scientific Publishers
• Subjects: Carcinoma, Non-Small-Cell Lung; Computed tomography (CT); Hematology, Oncology, and Palliative Medicine; Humans; Lung; Lung - diagnostic imaging; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - radiotherapy; Pulmonary function test (PFT); Radiation-induced lung damage (RILD); Respiratory Function Tests; Tomography, X-Ray Computed; Pulmonary function test (PFT); Computed tomography (CT); Lung; Radiation-induced lung damage (RILD); lung; computed tomography (CT); pulmonary function test (PFT); radiation-induced lung damage (RILD)

•Detailed RILD evolution described by objective radiological and pulmonary function measures.•RILD is associated with volume loss of the treated lung and contralateral lung hyperinflation.•Objective radiological findings might differentiate subjects with early versus late RILD.•Most patients develop...