Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis

• Published in: Circulation (New York, N.Y.) Vol. 144; no. 16; pp. 1308 - 1322
• Main Authors: Lee, Heon-Woo, Xu, Yanying, He, Liqun, Choi, Woosoung, Gonzalez, David, Jin, Suk-Won, Simons, Michael
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 19.10.2021
• Subjects: Animals; arteriovenous malformations; cell differentiation; cell lineage; endothelial cells; Endothelial Cells - metabolism; Humans; intravital microscopy; Mice; Mice, Transgenic; Neovascularization, Pathologic; vascular remodeling; cell differentiation; endothelial cells; intravital microscopy; vascular remodeling; cell lineage; arteriovenous malformations

Angiogenesis is a dynamic process that involves expansion of a preexisting vascular network that can occur in a number of physiological and pathological settings. Despite its importance, the origin of the new angiogenic vasculature is poorly defined. In particular, the primary subtype of endothelial...