Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults - Tampakakis, Emmanouil; Tabit, Corey E.; Holbrook, Monika; Linder, Erika A.; Berk, Brittany D.; Frame, Alissa A.; Bretón‐Romero, Rosa; Fetterman, Jessica L.; Gokce, Noyan; Vita, Joseph A.; Hamburg, Naomi M. (Journal of the American Heart Association, 2016)
Keywords: Activating Transcription Factor 6 - genetics; Activating Transcription Factor 6 - metabolism; Adult; Anticoagulants - administration & dosage; Biomarkers - metabolism; Emulsions - administration & dosage; endoplasmic reticulum stress; Endoplasmic Reticulum Stress - drug effects; Endoribonucleases - metabolism; Endothelial Cells - drug effects; Endothelial Cells - metabolism; endothelium; Female; free fatty acids; Gene Expression Regulation; Healthy Volunteers; Heparin - administration & dosage; Humans; Hyperemia - physiopathology; Infusions, Intravenous; Leg - blood supply; leukocyte; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Male; Microcirculation - drug effects; Original Research; Phospholipids - administration & dosage; Phospholipids - blood; Phosphorylation; Protein Phosphatase 1 - genetics; Protein Phosphatase 1 - metabolism; Protein Serine-Threonine Kinases - metabolism; Soybean Oil - administration & dosage; Soybean Oil - blood; Time Factors; Transcription Factor CHOP - genetics; Transcription Factor CHOP - metabolism; X-Box Binding Protein 1 - genetics; X-Box Binding Protein 1 - metabolism; Young Adult; endothelium; free fatty acids; endoplasmic reticulum stress; leukocyte