Circulating Cell-Free Nucleic Acids as Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer

• Published in: Biomedicines Vol. 11; no. 4; p. 1069
• Main Authors: Marin, Anelis Maria, Sanchuki, Heloisa Bruna Soligo, Namur, Guilherme Naccache, Uno, Miyuki, Zanette, Dalila Luciola, Aoki, Mateus Nóbrega
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2023; MDPI
• Subjects: Alcohol; Antigens; Biological markers; Biomarkers; Biopsy; Body mass index; Breast cancer; Cancer therapies; cell-free DNA; Chemotherapy; circulating cell-free nucleic acids; Diabetes; Diagnosis; diagnostic; Disease; Magnetic resonance imaging; Medical prognosis; Metastasis; miRNA; mRNA; Obesity; Pancreatic cancer; Prognosis; prognostic; Review; Risk factors; RNA; Smoking; Tomography; Tumor cells; Tumors; Weight control; United States; prognostic; cell-free DNA; pancreatic cancer; diagnostic; circulating cell-free nucleic acids

A lack of reliable early diagnostic tools represents a major challenge in the management of pancreatic cancer (PCa), as the disease is often only identified after it reaches an advanced stage. This highlights the urgent need to identify biomarkers that can be used for the early detection, staging, t...